Disease: Fusarium infection

Draft genome sequence data of Fusarium verticillioides strain REC01, a phytopathogen isolated from a Peruvian maize

Researchers sequenced the genome of a fungus that causes rot disease in corn plants, specifically from samples found in Peru. The fungus produces toxins that harm both human and animal health and reduces crop yields. By analyzing the fungus’s genetic code and comparing it with other strains, scientists can better understand how it causes disease and develop better strategies to protect corn crops.

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Fusarium Species Infecting Greenhouse-Grown Cannabis (Cannabis sativa) Plants Show Potential for Mycotoxin Production in Inoculated Inflorescences and from Natural Inoculum Sources

Researchers found that certain fungi called Fusarium species can infect cannabis flowers growing in greenhouses and produce harmful toxins called mycotoxins. These toxins, which can accumulate in dried cannabis buds, come from both direct infection and from nearby tall fescue grass plants growing outside the greenhouse. The study shows that high humidity conditions in greenhouses can promote fungal growth and toxin production, potentially affecting cannabis safety. Different cannabis varieties showed varying levels of toxin accumulation despite similar fungal infection rates.

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Discovery of novel targets for important human and plant fungal pathogens via an automated computational pipeline HitList

Researchers created a computer program called HitList that searches fungal DNA to find new targets for antifungal medications. The program identified 16 promising protein targets that could be attacked by new antifungal drugs, including 8 completely new targets never before considered. This discovery could help develop new antifungal treatments to fight drug-resistant fungal infections in both humans and crops.

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Liposomal amphotericin B prophylaxis in paediatrics: a systematic review

This review examined how well liposomal amphotericin B (a fungal medication) works to prevent serious fungal infections in children. Researchers looked at 20 studies involving over 2000 children and found that about 7% still developed fungal infections despite the medication, with common side effects being low potassium levels and liver problems. The main finding is that doctors use this medication in very different ways, and we need better research to figure out the best dosing strategy for children.

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