Disease: fungal bloodstream infection

Caspofungin therapy in prosthetic valve endocarditis and candidemia due to itraconazole-resistant Candida glabrata (Nakaseomyces glabratus): A case report

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A 13-year-old boy developed a serious fungal infection on his replacement heart valve after recent surgery. The fungal infection was caused by a type of yeast called Candida glabrata that was resistant to the initial antifungal medication. After testing revealed resistance and biofilm formation, doctors switched to caspofungin, a stronger antifungal drug, and the patient recovered successfully.

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Caspofungin therapy in prosthetic valve endocarditis and candidemia due to itraconazole-resistant Candida glabrata (Nakaseomyces glabratus): A case report

mycolabadmin

A 13-year-old boy developed a serious fungal infection of his heart valve after surgery. The infection was caused by a resistant yeast that didn’t respond to initial antifungal treatment. Doctors used molecular testing to identify the exact fungal species and tested how it responded to different medications. After switching to a different antifungal drug called caspofungin, the patient recovered completely and remained healthy.

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Glycan microarray analysis of Candida-related antibodies in human and mice sera guides biomarker discovery and vaccine development

mycolabadmin

Researchers used a special microarray technology to identify immune responses in blood samples from people infected with Candida yeast. They found that early infections trigger antibodies against certain sugar structures, while later infections produce different antibodies. Three specific sugar molecules showed promise as markers for diagnostic tests and vaccine development against dangerous yeast infections.

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