Disease: fungaemia

The Prognostic Value of (1→3)-β-D-Glucan in COVID-19 Patients with and Without Secondary Fungal Disease

During COVID-19 infection, a fungal marker called beta-D-glucan (BDG) in the blood can predict patient survival even without a diagnosed fungal infection. Researchers found that COVID-19 patients with high BDG levels had a 91% death rate if not treated with antifungal drugs, but this dropped to 50% when antifungal therapy was given. The high BDG levels trigger a strong inflammatory response in the body that worsens disease severity, making BDG a valuable warning sign for doctors treating critically ill COVID-19 patients.

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Enhancing antifungal stewardship: The educational and healthcare benefits of involving pharmacy students in audits

Researchers studied how involving pharmacy students in reviewing fluconazole (an antifungal medication) prescriptions could help hospitals improve their antifungal medication use and provide valuable training. Out of 145 prescriptions audited, about two-thirds were appropriate while one-third had issues like unnecessary use or drug interactions. Both the students and hospitals benefited significantly, with students gaining practical clinical experience while hospitals identified prescribing problems that could be improved.

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