Disease: dyslipidemia

A Randomized, Double-Blind, Placebo-Controlled Clinical Trial on the Effect of a Dietary Supplement Containing Dry Artichoke and Bergamot Extracts on Metabolic and Vascular Risk Factors in Individuals with Suboptimal Cholesterol Levels

Researchers tested a daily pill combining dried extracts from artichoke and bergamot plants to see if it could improve cholesterol levels and heart health in people with elevated cholesterol. After 12 weeks, people taking the supplement showed significant improvements in cholesterol levels, triglycerides, inflammation markers, and blood vessel function compared to those taking a placebo. The supplement was safe and well-tolerated, with minimal side effects, suggesting it could be a useful natural approach for managing cholesterol and related cardiovascular risk factors.

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Fermented Rice Bran: A Promising Therapeutic Agent Against High-Fat Diet-Induced Metabolic Disorders

Fermented rice bran, created by fermenting rice byproduct with beneficial bacteria, shows promise in helping manage weight and blood sugar levels in studies using rats on high-fat diets. The fermentation process increases the nutritional value of rice bran by boosting protein, fiber, and antioxidant content. Animals supplemented with fermented rice bran for 8 weeks showed improved cognitive function, better liver health, and improved lipid profiles compared to those on high-fat diets alone.

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Effects of Monascus pilosus SWM 008-Fermented Red Mold Rice and Its Functional Components on Gut Microbiota and Metabolic Health in Rats

Researchers studied whether fermented red mold rice could improve gut health in rats by examining changes in beneficial bacteria. The study found that red mold rice and its active compounds increased helpful bacteria like Akkermansia mucinophila without causing any harmful effects. These beneficial bacteria may support better digestion, metabolism, and overall health, suggesting fermented red mold rice could be useful as a functional food for maintaining a healthy gut.

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Nutraceutical supplement slim reshaped colon histomorphology and reduces Mucispirillum schaedleri in obese mice

Researchers tested a supplement called Slim containing natural compounds like berberine, coenzyme Q10, and beet pulp on obese mice. After 4 weeks, the supplement improved cholesterol and triglyceride levels, increased beneficial gut bacteria, and strengthened the intestinal barrier. The results suggest this combination of natural ingredients works together synergistically to improve gut health and metabolic function in obesity.

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The Role of Nutraceuticals and Probiotics in Addition to Lifestyle Intervention in the Management of Childhood Obesity—Part 1: Metabolic Changes

This review examines how natural compounds and beneficial bacteria can help obese children improve their metabolic health when combined with diet and exercise changes. Key findings show that supplements like white mulberry leaf extract and special fiber products can help reduce weight, improve blood sugar control, and lower cholesterol. The evidence suggests these natural interventions are promising but need more large-scale studies in children to confirm their effectiveness and optimal dosing.

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Exploring Therapeutic Potential of Pleurotus ostreatus and Agaricus bisporus Mushrooms against Hyperlipidemia and Oxidative Stress Using Animal Model

Oyster and white button mushrooms may help lower cholesterol and protect against heart disease. In a study using rats with high cholesterol, mushroom extracts reduced harmful cholesterol levels and improved the body’s natural defense against oxidative damage. These common, affordable mushrooms contain beneficial compounds that could be incorporated into diets as a natural way to support heart health and manage cholesterol.

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Enhancing Viability of Lactobacillus rhamnosus GG and Total Polyphenol Content in Fermented Black Goji Berry Beverage Through Calcium–Alginate Encapsulation with Hydrocolloids

Researchers developed a special technique to protect beneficial bacteria (Lactobacillus rhamnosus GG) in black goji berry juice so they survive the harsh conditions of the stomach and intestines. They used a coating made from alginate combined with ingredients like carrageenan or gelatin, which created a protective shield around the bacteria and helpful plant compounds. When this coated juice was taken with milk, the bacteria survived even better, making it a promising new way to deliver probiotics through plant-based beverages instead of traditional dairy products.

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Gut microbiota-mediated regulation of lipid metabolism by single herbal medicines: a review focused on cold/hot properties

This review examines how traditional Chinese herbal medicines can help regulate lipid metabolism and lower cholesterol by changing the composition of bacteria in our gut. Different herbs have different properties – some are considered cooling and others warming – and these properties affect which gut bacteria they increase or decrease. The review found that herbal medicines work best when matched to a person’s body constitution, and provides a framework for choosing the right herb based on whether someone has a heat-type or cold-type condition.

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Dietary Phytochemicals in Cardiovascular Disease Prevention and Management: A Comprehensive Review

This review examines how plant-based compounds called phytochemicals can help prevent and manage heart disease. These compounds, found in foods like berries, nuts, tea, garlic, and whole grains, work through multiple mechanisms including reducing inflammation, lowering cholesterol, and improving blood vessel function. The review highlights that while pharmaceutical treatments exist, dietary approaches using phytochemical-rich foods offer a cost-effective and sustainable way to support heart health.

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