Disease: dysbiosis

Lentinula edodes cultured extract intake alleviates long-term immune deregulation induced by early-life gut microbiota dysbiosis

Taking an extract from shiitake mushrooms (AHCC) during pregnancy and breastfeeding can help protect babies from the negative immune effects of antibiotics. Antibiotics given early in life damage the beneficial bacteria in the baby’s gut, leading to long-term immune problems. This study showed that shiitake extract helped restore healthy bacteria and reduced inflammation in mice exposed to antibiotics as infants, suggesting it could be used as a preventive measure for children who need antibiotics.

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Prebiotic property of tamarind seed kernel on Bifidobacterium animalis growth and biofilm formation

This study shows that tamarind seed kernel powder acts as a prebiotic, which are foods that feed beneficial bacteria in your gut. The research found that this powder promotes the growth of Bifidobacterium animalis, a helpful probiotic bacteria, and helps it form protective biofilms that adhere to intestinal walls. The tamarind seed powder actually worked better than inulin, a commonly used prebiotic, particularly at higher concentrations.

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Comparative Analysis of Freeze-Dried Pleurotus ostreatus Mushroom Powders on Probiotic and Harmful Bacteria and Its Bioactive Compounds

Researchers studied oyster mushrooms processed in different ways to understand their health benefits. The study found that cooked oyster mushroom powders can kill harmful bacteria and promote the growth of beneficial gut bacteria. These mushrooms also contain special particles called carbon nanodots that form during cooking and may enhance their health-promoting effects. The findings suggest oyster mushrooms could help maintain a healthy gut microbiota naturally.

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Glycosylation and sugar variations in tyrosol yield promising prebiotic-like effects

This study tested whether chemically modified versions of tyrosol, a natural compound found in olives and red wine, could boost beneficial gut bacteria better than the original form. Researchers gave mice three different versions: plain tyrosol, natural salidroside (tyrosol with glucose attached), and a lab-created version with galactose attached instead. The galactose version worked best, promoting the most beneficial bacteria like Bifidobacteria and reducing harmful bacteria, potentially offering health benefits similar to prebiotic supplements.

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Evaluation of the synbiotic effects of Saccharomyces cerevisiae and mushroom extract on the growth performance, digestive enzyme activity, and immune status of zebrafish danio rerio

Researchers tested whether combining a yeast called Saccharomyces cerevisiae with mushroom extract could improve the health and growth of zebrafish. The combination, called a synbiotic, significantly boosted fish growth by over 70%, enhanced their digestive function, and strengthened their immune system. This natural supplement approach shows promise for improving fish farming practices without requiring antibiotics.

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Microbes as Teachers: Rethinking Knowledge in the Anthropocene

Microbes have been the architects of life on Earth for nearly 4 billion years, managing oxygen production, nutrient cycles, and climate stability—yet we rarely recognize their wisdom. This paper argues we should treat microbes as teachers rather than mere subjects of study or exploitation. By reforming education, policy, and how we think about our relationship with microbial life, we can solve modern challenges like climate change and disease while learning to coexist with the microscopic majority that sustains all life.

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Microbes as Teachers: Rethinking Knowledge in the Anthropocene

This paper argues that microbes should be viewed as teachers offering crucial wisdom about how to solve today’s environmental crises. Rather than seeing microbes as passive subjects to be studied, the author proposes recognizing them as intelligent, collaborative partners that have successfully managed Earth’s systems for billions of years. The paper provides practical suggestions for changing education, policy, and how we design cities and agriculture to work with microbial processes rather than against them.

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