Disease: drug-resistant bacterial infections

The endophytic fungus Cosmosporella sp. VM-42 from Vinca minor is a source of bioactive compounds with potent activity against drug-resistant bacteria

Scientists discovered a fungus living inside a medicinal plant called Vinca minor that produces compounds capable of killing drug-resistant bacteria like MRSA. They isolated the main active compound, nectriapyrone, and found it effectively stops the growth of these dangerous bacteria in laboratory tests. The fungus appears to be a promising source of new antibacterial drugs that could help combat the growing problem of antibiotic-resistant infections.

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Strategies and materials for the prevention and treatment of biofilms

Biofilms are sticky communities of bacteria that form on medical devices and surfaces, making infections very difficult to treat with antibiotics. This review explains how biofilms develop in stages and describes different ways to stop them from forming or to destroy them once they exist. Solutions include special coatings on medical implants, natural plant extracts like essential oils, and engineered proteins called antimicrobial peptides that fight bacteria without creating antibiotic resistance.

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