Disease: Diet-induced obesity

Inonotus hispidus Protects against Hyperlipidemia by Inhibiting Oxidative Stress and Inflammation through Nrf2/NF-κB Signaling in High Fat Diet Fed Mice

Inonotus hispidus is an edible mushroom that may help treat obesity and high cholesterol by reducing fat levels and inflammation in the body. In mice fed a high-fat diet, the mushroom improved cholesterol profiles, reduced liver damage, and promoted beneficial gut bacteria. The beneficial effects appear to work through activating the body’s natural antioxidant defenses and reducing inflammation-causing proteins.

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Impacts of selenium enrichment on nutritive value and obesity prevention of Cordyceps militaris: A nutritional, secondary metabolite, and network pharmacological analysis

Researchers studied how adding selenium to Cordyceps militaris mushrooms affects their nutritional value and ability to prevent obesity. They found that selenium enrichment increased the mushroom’s carbohydrates and fiber content, and enhanced beneficial compounds like terpenoids and alkaloids. In mice fed a high-fat diet, both regular and selenium-enriched Cordyceps militaris reduced weight gain and improved metabolic health equally well. The study suggests these mushrooms work against obesity by using multiple active compounds that target different biological pathways simultaneously.

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