Disease: Diabetes

Exploring the Bioactive Potential of Calostoma insigne, an Endangered Culinary Puffball Mushroom, from Northeastern Thailand

This research investigated a rare, eye-shaped mushroom called Calostoma insigne that grows in Thai rainforests and is eaten by local people. Scientists confirmed traditional beliefs that the mushroom has health benefits, discovering it has antioxidant, anti-cancer, and anti-diabetic properties. The study also determined the best way to grow this mushroom in laboratories, which could help conserve the endangered species while providing a sustainable food and health resource.

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Impact of Packaging Variations on the Amino Acid Profile, Proximate Content, and Antinutritional Components of Tempeh from Jack Bean Sprouts

This study examines how wrapping tempeh made from jack bean sprouts in different materials affects its nutritional value. Researchers tested three packaging types—plastic, banana leaves, and teak leaves—over various fermentation periods. Results show that teak leaf packaging at 48 hours of fermentation produces tempeh with the highest protein and amino acid content while reducing harmful compounds like hydrogen cyanide to safe levels.

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Valorisation of fish scales and bones: a sustainable source of bioactive proteins and collagen for nutraceuticals

Fish scales and bones, usually thrown away as waste, contain valuable collagen and proteins that can improve skin, joints, and overall health. New extraction methods can recover these beneficial compounds efficiently while being environmentally friendly. Studies show that taking fish collagen supplements daily can improve skin appearance, reduce joint pain, and lower blood pressure, making them a sustainable and natural health solution.

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Valorization and Environmental Impacts of Pecan Waste: A Critical Review

Pecan shells, which make up about half of the pecan nut and are usually discarded, contain valuable compounds with health-promoting properties like antioxidants and anti-inflammatory agents. These shells can be transformed into useful products including ingredients for food supplements and medicines, activated carbon for cleaning water, materials for making eco-friendly plastics, and energy sources. By converting pecan waste into valuable products instead of throwing it away, communities can reduce environmental pollution, improve public health, and create economic opportunities while supporting sustainable farming practices.

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The Molecular Mechanism of Polysaccharides from Polygonatum cyrtonema Hua in Improving Hyperuricemia by Regulating Key Targets of Uric Acid Metabolism in Mice

This research demonstrates that a traditional Chinese medicinal plant called Polygonatum cyrtonema contains beneficial polysaccharides that can help lower high uric acid levels in the blood, which is a major cause of gout and kidney disease. The study found that these polysaccharides work by reducing the enzyme that produces uric acid and helping the kidneys excrete more of it, while also reducing inflammation. Importantly, this natural treatment protected kidney tissue better than the standard pharmaceutical drug allopurinol, suggesting it could be a safer long-term option for managing high uric acid levels.

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Universal Platform Based on Carbon Nanotubes Functionalised with Carboxylic Acid Groups for Multi-Analyte Enzymatic Biosensing

Scientists have created a tiny biosensor platform using carbon nanotubes that can detect multiple important molecules in blood and food simultaneously. The sensor uses special enzymes that recognize glucose, lactate, glutamate, and dopamine, making it useful for monitoring diabetes, fatigue levels, and brain chemistry. By adding another enzyme called catalase, the sensor works even better and across a wider range of concentrations. Tests on real blood and food samples show the sensor accurately measures these important biomarkers, making it potentially valuable for both health monitoring and food quality testing.

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Arsenic Stress Resistance in the Endophytic Fungus Cladosporium cladosporioides: Physiological and Transcriptomic Insights into Heavy Metal Detoxification

A special fungus called Cladosporium cladosporioides, found living inside the roots of Gentiana yunnanensis (a traditional Chinese medicine herb), can tolerate extremely high levels of arsenic. Researchers discovered that this fungus protects itself from arsenic poisoning by storing arsenic mostly in its cell walls, converting toxic arsenic into less harmful forms, and activating its antioxidant defense systems. This discovery could help reduce arsenic contamination in medicinal herbs and lead to new methods for cleaning arsenic-polluted soil.

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Whole genome sequencing and annotations of Trametes sanguinea ZHSJ

Scientists have completely mapped the genetic code of Trametes sanguinea, a medicinal mushroom used in traditional Chinese medicine. They identified over 10,000 genes and analyzed how this mushroom produces compounds that fight tumors, boost immunity, protect the heart, and fight viruses. This genetic map will help researchers understand how to produce these beneficial compounds and develop new medicines from this mushroom.

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Towards engineering agaricomycete fungi for terpenoid production

Mushroom-forming fungi, particularly species like shiitake and oyster mushrooms, naturally produce valuable compounds called terpenoids used in medicines, food, and cosmetics. Scientists are learning to genetically engineer these fungi to produce even larger amounts of these beneficial compounds, potentially making them as important to biotechnology as baker’s yeast and mold have been historically. This could create new sustainable sources for medicinal compounds and industrial chemicals.

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