Disease: Diabetes

Effects and molecular mechanism of endophytic elicitors on the accumulation of secondary metabolites in medicinal plants

This review explains how beneficial fungi living inside medicinal plants can boost the production of healing compounds. These endophytic fungi act as natural triggers that activate the plant’s own defense systems, causing it to produce more of the valuable medicinal substances used in traditional and modern medicine. By understanding how this process works, scientists can develop better methods to grow medicinal plants and produce natural drugs more sustainably without depleting wild plant populations.

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Diet-Derived Advanced Glycation End-Products (AGEs) Induce Muscle Wasting In Vitro, and a Standardized Vaccinium macrocarpon Extract Restrains AGE Formation and AGE-Dependent C2C12 Myotube Atrophy

This research shows that processed foods high in sugar and fat create harmful compounds called AGEs that can cause muscle loss and weakness. Cranberry extract, which contains natural antioxidants, was found to be particularly effective at blocking AGE formation and preventing muscle cell damage. The study suggests that eating foods containing cranberry extract might help prevent age-related muscle loss and the negative effects of unhealthy Western diets on muscle health.

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Marine-derived Acremonium strain prioritization using untargeted metabolomics approach for the identification of cytotoxic cyclic depsipeptides

Researchers discovered five potent anti-cancer compounds from Arctic fungi called Acremonium strains. Using advanced chemical analysis techniques, they identified and tested these cyclic depsipeptides against various cancer cell types. The most active compound showed promising results against breast cancer and melanoma cells with extremely low concentrations needed for effect. These findings suggest Arctic microorganisms could be valuable sources for developing new cancer treatments.

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Novel chia (Salvia Hispanica L.) residue-based substrate formulations for oyster mushroom (Pleurotus ostreatus) cultivation

Researchers discovered that leftover plant material from chia seed production can be used to grow oyster mushrooms with excellent nutritional value. When chia residues were combined with rice straw in the right proportions, they produced mushrooms with higher protein content, more beneficial compounds, and better yields than traditional growing methods. This finding helps solve two problems at once: it creates a valuable use for chia farming waste while producing highly nutritious mushrooms for human consumption.

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Influence of Culture Conditions on Bioactive Compounds in Cordyceps militaris: A Comprehensive Review

This review examines how growing conditions affect the medicinal compounds produced by Cordyceps militaris mushrooms. The research shows that factors like light exposure, specific nutrient combinations, and growing on insect-based substrates can significantly boost production of beneficial compounds like cordycepin. These findings suggest ways to produce more effective and affordable medicinal mushroom products for use in supplements and pharmaceuticals.

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Traditional uses, chemical components and pharmacological activities of the genus Ganoderma P. Karst.: a review

Ganoderma, a medicinal fungus used in traditional medicine for over 2000 years, contains many beneficial compounds including triterpenes and polysaccharides. Scientific research has confirmed its effectiveness in treating various conditions including cancer, diabetes, infections, and inflammation. The fungus works by boosting the immune system, reducing oxidative stress, and directly inhibiting disease-causing organisms. Modern cultivation methods have made Ganoderma products widely available as supplements and medicines worldwide.

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Bioactive Steroids Bearing Oxirane Ring

This research reviews special types of steroids that contain oxirane rings, which are highly reactive chemical structures found in marine organisms, fungi, and plants. These compounds have shown promise in treating various diseases including cancer, inflammation, and high cholesterol. Scientists used computer software to predict and analyze the biological activities of over 150 different epoxy steroids, categorizing them by the position of their oxirane ring. The findings suggest these natural compounds could be valuable for developing new medicines and understanding how chemicals interact with our bodies.

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Critical review on chemical compositions and health-promoting effects of mushroom Agaricus blazei Murill

Agaricus blazei Murill is an edible mushroom that contains many beneficial compounds including polysaccharides, vitamins, and minerals. Research shows it may help boost the immune system, reduce blood sugar levels, protect the liver, fight inflammation, and even have anti-cancer properties. While animal studies show promising results, more human clinical trials are needed to confirm its health benefits and establish proper dosing for therapeutic use.

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FTIR Characterization and Bioactivity Assessment of Cinnamomum camphora Essential Oil: Antioxidant, Anti-Enzymatic, and Antifungal Properties Against Phytopathogens

Camphor tree essential oil has been studied for its ability to fight fungal diseases that harm crops and its potential health benefits. The research found that this natural oil completely stops the growth of several harmful fungi at high concentrations, making it a promising eco-friendly alternative to synthetic pesticides. The oil also showed antioxidant properties and may help regulate blood sugar levels, suggesting uses in both agriculture and medicine.

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Awareness and perception of invasive fungal diseases among the Nigerian population

This study found that very few Nigerians (only about 19%) are aware of serious fungal infections like candidiasis and aspergillosis, and most people don’t understand how dangerous these diseases can be. The researchers surveyed over 1,200 people and discovered that people with more education and higher incomes were more likely to know about these infections. The findings suggest that Nigeria urgently needs public health campaigns and education programs to help people recognize fungal diseases early so they can get proper treatment.

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