diabetes mellitus – mycolab.ai

Effects of adding food ingredients rich in dietary fiber and polyphenols on the microstructure, texture, starch digestibility and functional properties of Chinese steamed bun

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Researchers created an improved version of Chinese steamed bun by adding dragon fruit, kudzu root, and a medicinal mushroom called Hericium erinaceus. This new bun has much more fiber and antioxidants, and importantly, it causes much smaller increases in blood sugar after eating compared to traditional steamed buns. The study shows it can help promote beneficial gut bacteria and may be beneficial for people managing diabetes and metabolic health.

Therapeutic and Nutraceutical Potential of Sargassum Species: A Narrative Review

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Sargassum is a type of ocean seaweed that has been used in traditional medicine for centuries and contains compounds that may help fight inflammation, oxidative stress, viruses, and bacteria. Scientists have discovered that different Sargassum species produce nearly 200 different bioactive compounds with potential health benefits ranging from reducing arthritis symptoms to supporting immune function. While Sargassum can accumulate harmful heavy metals like arsenic from seawater, researchers have developed effective cleaning methods to remove these contaminants while preserving the beneficial compounds. This makes Sargassum a promising sustainable source of natural medicines and health supplements.

The Antioxidant Properties of Mushroom Polysaccharides can Potentially Mitigate Oxidative Stress, Beta-Cell Dysfunction and Insulin Resistance

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This research review explores how mushroom compounds called polysaccharides may help manage diabetes by reducing harmful stress on cells caused by high glucose levels. Scientists found that 104 different mushroom polysaccharides have anti-diabetic properties and can protect insulin-producing cells in the pancreas. These natural compounds show promise as a complementary treatment to conventional diabetes medications, potentially with fewer side effects than synthetic drugs.

Valorization of Hericium erinaceus By-Products for β-Glucan Recovery via Pulsed Electric Field-Assisted Alkaline Extraction and Prebiotic Potential Analysis

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This research shows how scientists can extract beneficial compounds called β-glucans from leftover Lion’s Mane mushroom material using electrical pulses and alkaline treatment. These extracted compounds work like prebiotics, feeding and promoting the growth of beneficial bacteria in your gut, which then produce healthy fatty acids that support digestive health. The method is environmentally friendly and could help food companies make functional ingredients from mushroom waste.

Investigating the Knowledge of Prebiotics, Probiotics, and Synbiotics That May Help to Improve the Gut-Organ Axis Function in Middle-Aged and Older Adults

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This study examined what middle-aged and older adults know about probiotics, prebiotics, and synbiotics—special food components that can improve gut health. Researchers found that many people had little knowledge about these products, even though they may help with various health conditions including heart disease and mental health. After giving people an educational information sheet about gut biotics, their knowledge significantly improved, suggesting that simple education can help people make better choices about their digestive health.

In vitro fermentation characteristics and prebiotic activity of herbal polysaccharides: a review

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This review explores how plant-based polysaccharides from traditional herbs can benefit our health by feeding good bacteria in our gut. When these polysaccharides are fermented by our gut microbiota, they break down into smaller compounds that produce short-chain fatty acids, which have anti-inflammatory and immune-boosting effects. The research shows that different herbs have different structures that are recognized by specific beneficial bacteria, which suggests we can develop personalized functional foods tailored to promote specific health benefits.

Hypoglycemic Effect of Edible Fungi Polysaccharides Depends on Their Metabolites from the Fermentation of Human Fecal Microbiota

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Edible mushrooms like Ganoderma lucidum, cordyceps, shiitake, and poria contain beneficial compounds called polysaccharides that may help control blood sugar. When these polysaccharides are digested by beneficial gut bacteria, they produce eight special metabolites that enhance the body’s ability to use glucose and improve insulin sensitivity. The research identified specific bacteria, such as Faecalibacterium and Coprococcus, that produce these beneficial metabolites, suggesting that measuring these markers could help evaluate which mushroom polysaccharides work best for diabetes prevention.

The Impact of Psilocybin on High Glucose/Lipid-Induced Changes in INS-1 Cell Viability and Dedifferentiation

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Researchers tested whether psilocybin, a compound from magic mushrooms, could protect pancreatic β-cells (which produce insulin) from damage caused by high glucose and fat levels. Using laboratory cells, they found that psilocybin reduced β-cell death by preventing apoptosis and showed promise in reducing dedifferentiation (when cells lose their specialized functions). However, psilocybin didn’t restore the cells’ ability to respond to glucose by releasing insulin.

Gut microbiota-mediated regulation of lipid metabolism by single herbal medicines: a review focused on cold/hot properties

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This review examines how traditional Chinese herbal medicines can help regulate lipid metabolism and lower cholesterol by changing the composition of bacteria in our gut. Different herbs have different properties – some are considered cooling and others warming – and these properties affect which gut bacteria they increase or decrease. The review found that herbal medicines work best when matched to a person’s body constitution, and provides a framework for choosing the right herb based on whether someone has a heat-type or cold-type condition.

From natural laboratory to drug discovery: Chemical structures, bioactivities, and biosynthesis of meroterpenoids from Ganoderma species

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This review examines special compounds called meroterpenoids found in Ganoderma mushrooms (commonly known as Reishi). Scientists have identified over 350 of these compounds from 14 different Ganoderma species. These compounds show promise for treating various health conditions including cancer, kidney disease, diabetes, and inflammatory disorders. The researchers also propose how these compounds are made inside the mushroom, which could help scientists produce them more efficiently for medical use.

Disease: diabetes mellitus