Researchers in Finland studied how a fast DNA test (PCR) can detect fungal skin infections better than traditional slow culture methods. The new test, called DermaGenius, gives results in just 16 hours instead of 19 days. By 2022, most fungal infection samples were tested using this faster method, which helps doctors treat patients quickly without unnecessary medications.
Scientists are exploring nano-graphene oxide, a microscopic material made from graphene, as a new treatment for serious lung fungal infections. These tiny particles can kill fungal cells through multiple mechanisms and deliver antifungal drugs directly to infection sites while reducing harmful side effects. Researchers found that graphene oxide can be combined with existing antifungal medications to make them work better and even help overcome drug-resistant fungal infections.
Athlete’s foot and nail fungal infections caused by Trichophyton rubrum are difficult to treat because the fungus forms protective biofilms that resist antifungal medications. This research shows that enzymes like cellulase, protease, and amylase can break down these biofilm barriers when used alone or in combination. The combination approach was most effective, suggesting that enzyme-based treatments could become useful additions to current fungal infection therapies.
This study examined fungal skin infections caused by dermatophytes in a Moroccan hospital over four years, analyzing 950 samples. The researchers found that nail infections (onychomycosis) were most common, particularly in people over 50 years old, while scalp infections mainly affected children. The fungus Trichophyton rubrum was responsible for most infections, though Microsporum canis increasingly caused scalp infections, likely due to increased pet ownership in Morocco. The study emphasizes the importance of proper laboratory testing to identify the specific fungus and choose appropriate treatment.
Researchers discovered that a protein called TrPtk2 helps dermatophytes resist terbinafine, a common antifungal medicine. They found that blocking this protein makes the fungus more susceptible to terbinafine. Additionally, they discovered that omeprazole, a stomach medication approved for human use, can be combined with terbinafine to make it more effective against resistant fungal infections.