Disease: COVID pneumonia

Atypical Adult-onset Still’s disease with flagellate morphology in a patient with skin of color

A 28-year-old African American woman was diagnosed with Adult-onset Still’s disease, a rare inflammatory condition causing fever, joint pain, and skin rashes. Her rash had an unusual linear, stripe-like pattern with dark pigmentation that doesn’t typically appear in standard descriptions of this disease. She was successfully treated with anakinra and later tocilizumab, medications that reduce inflammation, leading to complete symptom resolution and sustained improvement over nine months.

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Phaeohyphomycosis due to Nigrograna chromolaenae in a cardiac transplant patient

A 71-year-old heart transplant patient developed a slowly growing bump on his finger caused by a rare fungus called Nigrograna chromolaenae. Doctors initially tried common antifungal medications that didn’t work well, but the patient improved significantly when switched to posaconazole treatment. This is the first documented case of this particular fungus infecting a human, highlighting the importance of accurately identifying fungi to choose the right treatment.

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