Disease: COVID-19

Introduction to Traditional Medicine and Their Role in Prevention and Treatment of Emerging and Re-Emerging Diseases

This article explores how traditional medicine systems like Ayurveda and Chinese Medicine can help prevent and treat infectious diseases, including COVID-19. These ancient healing systems use natural herbs and lifestyle changes to boost immunity and fight infections more holistically. Scientific evidence shows that natural compounds like curcumin from turmeric have real antiviral and anti-inflammatory properties. By combining traditional knowledge with modern research, we may develop better treatments for emerging diseases.

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Natural Ingredients to Improve Immunity

Many natural ingredients from plants, mushrooms, and other sources can boost your immune system and help fight infections. These include well-known items like garlic, ginger, and vitamin C, as well as lesser-known compounds like β-glucans from mushrooms and melatonin from plant sources. Proper nutrition with adequate vitamins and minerals is crucial for maintaining a strong immune system that protects you from disease without overreacting and causing autoimmune problems.

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Time- and temperature-dependent Pentraxin 3 stability in serum and bronchoalveolar lavage fluid samples

Pentraxin 3 is a protein marker that helps doctors detect serious fungal infections. This study tested how well this marker stays stable in blood and lung fluid samples when stored at different temperatures over long periods. The results show that samples should be kept frozen at −20°C or −80°C to preserve the marker, but samples left at room temperature or warmer are quickly damaged and unreliable for testing.

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Fruiting body-associated Pseudomonas contact triggers ROS-mediated perylenequinone biosynthesis in Shiraia mycelium culture

Scientists discovered that bacteria living inside medicinal mushroom fruiting bodies can trigger the production of powerful healing compounds called perylenequinones through direct physical contact. These compounds are being used to fight cancer and harmful bacteria through a therapy called photodynamic therapy. The study shows that when bacteria touch the mushroom’s cells, it causes the mushroom to produce more of these therapeutic compounds by creating controlled stress that activates specific genes.

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Targeting SARS-CoV-2 with Chaga mushroom: An in silico study toward developing a natural antiviral compound

This study used computer modeling to investigate whether Chaga mushroom components can bind to and potentially block the coronavirus spike protein that SARS-CoV-2 uses to infect cells. The researchers found that three active compounds in Chaga—beta glycan, betulinic acid, and galactomannan—attached strongly to the virus’s binding sites in ways similar to known antiviral molecules. Beyond blocking viral entry, Chaga also has immune-boosting and anti-inflammatory properties that could help prevent the dangerous cytokine storm associated with severe COVID-19.

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Comparison of Ergosterol and Vitamin D2 in Mushrooms Agaricus bisporus and Cordyceps militaris Using Ultraviolet Irradiation Directly on Dry Powder or in Ethanol Suspension

This study shows that exposing mushroom powder suspended in ethanol to ultraviolet light effectively converts ergosterol (a natural compound in mushrooms) into vitamin D2, which is essential for bone health and immunity. The optimal treatment involves UV-C light exposure for 120 minutes at a specific distance, producing about 15 times more vitamin D2 than direct irradiation of dry mushroom powder. After removing the ethanol, these treated mushrooms could serve as a practical natural source of vitamin D for people with deficiency.

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Epidemiology of mucormycosis in COVID-19 patients in northwest Iran: Rhizopus arrhizus as the predominant species

During the COVID-19 pandemic, a dangerous fungal infection called mucormycosis was found in 63 patients in northwestern Iran. The infection was caused mainly by a fungus called Rhizopus arrhizus and most commonly affected the sinuses and brain. Most patients had been given high-dose steroids to treat their COVID-19, which weakened their immune systems and increased their risk of this serious fungal infection, especially those with diabetes.

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Mycobiome analyses of critically ill COVID-19 patients

This study examined fungal infections in severely ill COVID-19 patients treated in intensive care units across Europe. Researchers found that a dangerous mold called Aspergillus fumigatus was more common in patients who died and less common in those treated with azole antifungal drugs. The findings suggest that giving antifungal medications to critically ill COVID-19 patients when they arrive at the hospital might help prevent fungal-related deaths.

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Comment on Subhadra et al. Significant Broad-Spectrum Antiviral Activity of Bi121 against Different Variants of SARS-CoV-2

This is a scientific critique of a recent study claiming that a plant extract called Bi121 has antiviral properties against SARS-CoV-2. The author raises important concerns about how the plant material was prepared and characterized, noting that the chemical fingerprint appears suspiciously identical to a previously published extract, and that the identification of the active ingredient relies on incomplete evidence. The critique calls for more rigorous scientific methods to verify the original study’s findings.

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