COVID-19 – mycolab.ai

Unveiling roles of beneficial gut bacteria and optimal diets for health

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Your gut bacteria are tiny living organisms that help digest food, support your immune system, and influence your overall health. Eating foods rich in fiber, fermented products like yogurt and kimchi, and colorful fruits and vegetables helps grow these beneficial bacteria. When your gut bacteria become unbalanced, it can lead to inflammation and various diseases, but eating the right foods can restore balance and improve your health.

The effectiveness of interventions to reduce the transmission of acute respiratory infections in care homes: a systematic review

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This systematic review examined effective ways to prevent respiratory infections like flu and COVID-19 in care homes where elderly residents live. The researchers found that antiviral medications like oseltamivir can halve the risk of influenza even in vaccinated residents if given within 7 days of detecting a case. High-dose vitamin D supplementation (100,000 IU monthly) reduced respiratory infection risk by 40%. Educational programs to improve staff hygiene practices showed mixed results, while other supplements like probiotics did not significantly help.

Prognostic model for gastric cancer patients with COVID-19 and network pharmacology study on treatment by lentinan

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This study investigated how lentinan, a compound from shiitake mushrooms, might help treat patients who have both gastric cancer and COVID-19. Researchers identified five genes that predict patient outcomes and found that lentinan may work by controlling immune cell activity and reducing inflammation. The study suggests lentinan could be a useful additional treatment for this challenging combination of diseases, though more research is needed.

Editorial: Raising the bar: advancing therapeutic strategies for fighting communicable and noncommunicable diseases

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Scientists are developing new ways to fight dangerous infections caused by bacteria, viruses, and drug-resistant pathogens. Recent discoveries include safer uses of existing drugs, better dosing strategies tailored to individual patients, and effective combination therapies that reduce antibiotic resistance. These advances represent important progress in treating serious infectious diseases like COVID-19, tuberculosis, and bacterial infections.

Long-COVID symptoms improved after MDMA and psilocybin therapy: A case report

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A 41-year-old woman with Long-COVID experienced severe symptoms including fatigue, depression, anxiety, headaches, and brain fog that didn’t improve with traditional treatments. She decided to try psilocybin mushrooms and MDMA with guidance from a therapist. After multiple dosing sessions over several months, she reported roughly 80-90% improvement in her symptoms and was able to return to work and resume her studies. While this single case is promising, more research is needed to determine whether these psychedelics are truly safe and effective for Long-COVID.

Medicinal Mushrooms as Multicomponent Mixtures—Demonstrated with the Example of Lentinula edodes

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Shiitake mushrooms are more than just tasty food—they contain numerous compounds that work together to improve health. Unlike single isolated drugs, whole mushroom preparations offer multiple benefits including boosting immunity, protecting the heart, and potentially supporting cancer treatment. These mushrooms have been used safely in Asian medicine for over 2000 years and are becoming recognized worldwide for their health-promoting properties.

Dissecting the difference between positive and negative brain health sentiment using X data

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This study examined over 390,000 posts on X (formerly Twitter) about brain and health to understand how people express positive and negative feelings. Researchers found that negative posts were shared more often and were linked to serious health concerns like COVID-19 and brain inflammation. People expressing negative sentiment mentioned medications like lorazepam and comfort foods like pizza, while those with positive sentiment discussed resilience, mindfulness, and different medications. The research highlights both the benefits and dangers of sharing health information on social media.

Indole-Based Compounds as Potential Drug Candidates for SARS-CoV-2

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Scientists are searching for new treatments for COVID-19 by studying indole-containing compounds, which are found in many plants and can be made in laboratories. Some approved drugs with indole structures, like the antiviral drug Arbidol, have been repurposed to fight COVID-19. Researchers are also designing new indole compounds and using computer simulations to predict which ones might work best against the virus’s key proteins.

A Review of Novel Antioxidant Ergothioneine: Biosynthesis Pathways, Production, Function and Food Applications

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Ergothioneine is a powerful natural antioxidant found mainly in mushrooms that protects cells from damage and may help prevent diseases like Alzheimer’s and heart disease. Currently, producing ergothioneine from mushrooms is expensive and slow, but scientists have developed faster fermentation methods using engineered microbes that could make it cheaper and more available. This compound can be added to foods and supplements to boost health benefits, and researchers are exploring its use beyond seafood to other food products like meat and baked goods.

Thin-Layer Chromatography (TLC) in the Screening of Botanicals–Its Versatile Potential and Selected Applications

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This review shows how thin-layer chromatography (TLC), a simple laboratory technique, is invaluable for analyzing plant materials. TLC helps scientists identify which plants are related to each other, find beneficial compounds in herbs, ensure herbal medicines are pure and safe, and track illegal psychoactive plants. Despite being less glamorous than modern equipment, TLC remains practical, affordable, and effective for everyday botanical analysis.

Disease: COVID-19