Disease: colorectal cancer

Fruit and Vegetable Processing Waste as Potential Raw Material for Food Enrichment With Dietary Fiber

This study examined the fiber content of leftover materials from processing fruits and vegetables, finding that pomace (processing waste) is an excellent source of dietary fiber. Chokeberries and blackcurrants were found to have particularly high fiber levels, while apples and carrots were rich in soluble fiber types. These waste products can be used to create nutritious fiber-enriched foods and supplements, providing both environmental benefits by reducing waste and health benefits through increased dietary fiber consumption.

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Marine-Derived Enterococcus faecalis HY0110 as a Next-Generation Functional Food Probiotic: Comprehensive In Vitro and In Vivo Bioactivity Evaluation and Synergistic Fermentation of Periplaneta americana Extract Powder

Scientists discovered a beneficial bacteria called Enterococcus faecalis HY0110 from bluefin tuna that could help protect gut health and fight harmful pathogens better than current probiotics. This marine bacteria produces important compounds like acetic acid that kill disease-causing bacteria, reduce inflammation in inflammatory bowel disease, and even slows cancer cell growth. When fermented with cockroach powder, it creates powerful health-boosting compounds that could make functional foods more effective for managing digestive diseases and supporting overall wellness.

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Chemical Content and Cytotoxic Activity on Various Cancer Cell Lines of Chaga (Inonotus obliquus) Growing on Betula pendula and Betula pubescens

This study examined chaga mushroom, a traditional medicine used against cancer, grown on two types of birch trees. Researchers tested chaga extracts on 31 different cancer cell types and found they were moderately effective at inhibiting cancer cell growth, particularly against liver and thyroid cancers. The chaga from silver birch (B. pendula) worked slightly better than that from downy birch (B. pubescens) due to higher levels of a compound called inotodiol.

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Bacterial–Fungal Interactions: Mutualism, Antagonism, and Competition

Bacteria and fungi in animal bodies interact in three main ways: they help each other (mutualism), fight each other (antagonism), or compete for resources. These interactions happen in the gut, rumen, and skin of animals. Understanding how to balance these relationships can help create better probiotics and natural alternatives to antibiotics for treating infections and improving animal health.

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Harnessing the Nutritional Value, Therapeutic Applications, and Environmental Impact of Mushrooms

Mushrooms are nutritious superfoods packed with protein, fiber, vitamins, and minerals that support overall health. They contain special compounds that can fight inflammation, boost immunity, and help prevent serious diseases like cancer and diabetes. Beyond eating them, mushrooms are being used to make medicines, cosmetics, and animal feed, while also helping clean up polluted environments. Regular consumption of mushrooms offers significant health benefits and can be a valuable addition to any healthy diet.

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Benefits, side effects, and uses of Hericium erinaceus as a supplement: a systematic review

Lion’s Mane mushroom shows promising benefits for brain health, potentially improving memory and reducing symptoms of anxiety and depression. It may help prevent cancer by triggering cancer cell death and supports digestive health by promoting beneficial gut bacteria. While generally safe, some people experience mild side effects like stomach discomfort or headaches, making it an accessible supplement for overall wellness.

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Honeybee associated Aspergillus niger AW17 as a source of selective anticancer compounds with cytotoxicity evaluation in human cancer cell lines

Scientists discovered that a fungus found in honeybees can produce compounds that effectively kill cancer cells while leaving healthy cells largely unharmed. The fungus (Aspergillus niger AW17) contains unique bioactive compounds including high levels of oleic acid and a rare compound called pachymic acid. When tested against four types of human cancer cells, the fungal extract was particularly effective against liver and colorectal cancer. This finding suggests that exploring specialized environments like beehives could lead to new cancer treatments with fewer side effects.

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A Novel Erinacine S Derivative from Hericium erinaceus Overcomes Chemoresistance in Colorectal Cancer Cells by Enhancing TRAIL/TNFR1/DR5 Expression through Histone Acetylation

This study shows that erinacine S, a natural compound from Lion’s Mane mushrooms, can help overcome drug resistance in colorectal cancer cells. The compound works by activating pathways that trigger cancer cell death and by modifying how genes are expressed at the molecular level. In both laboratory experiments and animal models, erinacine S successfully stopped tumor growth and killed resistant cancer cells, suggesting it could be a promising natural treatment for patients with hard-to-treat colorectal cancer.

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How Should the Worldwide Knowledge of Traditional Cancer Healing Be Integrated with Herbs and Mushrooms into Modern Molecular Pharmacology?

This comprehensive review explores how traditional healing practices from around the world use plants and mushrooms to treat cancer. The authors examine thousands of plant species and their active compounds that show promise in fighting various types of cancer through multiple mechanisms like stopping cancer cell growth and triggering cell death. The review emphasizes that proper scientific validation, standardization, and safety testing can help integrate these traditional remedies into modern cancer treatment alongside conventional chemotherapy.

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