Chronic kidney disease

Mediation and moderation by inflammation and dietary patterns in heavy metal exposure effects on kidney function

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This study found that exposure to heavy metals like lead and cadmium damages kidney function by triggering inflammation in the body. Interestingly, what you eat matters significantly – a healthy diet can help protect your kidneys from heavy metal damage, while an unhealthy, pro-inflammatory diet makes the damage worse. The research suggests that eating better may be an effective way to reduce kidney disease risk from environmental pollution exposure.

Functional Components from the Liquid Fermentation of Edible and Medicinal Fungi and Their Food Applications in China

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Mushroom mycelium grown in liquid fermentation produces many beneficial compounds like polysaccharides and proteins that support immune function and may help fight cancer and oxidative stress. These fermented mushroom products can be added to foods, beverages, and health supplements to boost their nutritional value and health benefits. Studies show that fermented mushroom mycelium sometimes contains higher levels of beneficial compounds compared to whole mushroom fruiting bodies, making it a promising ingredient for functional foods and health products.

Association of the use of nonfood prebiotics, probiotics, and synbiotics with total and cause-specific mortality: a prospective cohort study

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This study of over 53,000 American adults found that people taking nonfood supplements containing prebiotics, probiotics, or synbiotics had significantly lower risks of dying from any cause, heart disease, cancer, or other causes compared to those who didn’t take these supplements. The benefits were particularly strong in women and people without high blood pressure. These findings suggest that these supplement types may play an important role in preventing early death.

Environmental pollution and its impact on hypertension: a review

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This review explains how environmental pollution from cars, factories, and industrial processes contributes to high blood pressure. Various pollutants like fine dust particles, heavy metals, and chemical vapors damage blood vessels and trigger inflammation in the body, leading to hypertension. Women after menopause and older adults are particularly vulnerable to these effects. The review emphasizes the importance of government policies, public education, and personal awareness in reducing pollution exposure and protecting heart health.

A comprehensive overview of the effects of probiotics, prebiotics and synbiotics on the gut-brain axis

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This comprehensive review examines how probiotics (beneficial live bacteria), prebiotics (food for beneficial bacteria), and synbiotics (combinations of both) can influence communication between the gut and brain. These interventions can produce beneficial compounds like GABA and serotonin, strengthen the gut barrier, and reduce inflammation, potentially helping with mood, anxiety, cognition, and various digestive disorders. However, effects vary greatly depending on the specific strain used, dosage, and individual differences in gut bacteria, and more large-scale studies are needed to confirm long-term clinical benefits.

Innovative Bioactive Nanofibrous Materials Combining Medicinal and Aromatic Plant Extracts and Electrospinning Method

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This research explains how scientists use a technique called electrospinning to create tiny, beneficial fibers from medicinal plants. By combining plant extracts like turmeric with biodegradable polymers, researchers create advanced materials that can deliver medicine, promote wound healing, and fight bacteria. These innovative fibers represent a natural approach to healthcare, bringing ancient plant wisdom into modern nanotechnology for practical medical applications.

Impact of Cordyceps sinensis on coronary computed tomography angiography image quality and renal function in a beagle model of renal impairment

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This study tested whether a traditional mushroom supplement called Cordyceps sinensis could protect kidney function in dogs undergoing heart imaging tests that use contrast dye. Researchers found that dogs receiving Cordyceps sinensis combined with lower doses of contrast dye maintained good image quality while showing better kidney function afterward compared to controls receiving conventional contrast doses without the supplement. Advanced imaging techniques confirmed that Cordyceps sinensis helped protect kidney tissue from damage caused by the contrast material.

From natural laboratory to drug discovery: Chemical structures, bioactivities, and biosynthesis of meroterpenoids from Ganoderma species

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This review examines special compounds called meroterpenoids found in Ganoderma mushrooms (commonly known as Reishi). Scientists have identified over 350 of these compounds from 14 different Ganoderma species. These compounds show promise for treating various health conditions including cancer, kidney disease, diabetes, and inflammatory disorders. The researchers also propose how these compounds are made inside the mushroom, which could help scientists produce them more efficiently for medical use.

Biosensors Based on Phenol Oxidases (Laccase, Tyrosinase, and Their Mixture) for Estimating the Total Phenolic Index in Food-Related Samples

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This review discusses specialized sensors that can quickly measure the total amount of beneficial plant compounds (phenolics) in foods like tea, wine, coffee, and fruits. These biosensors use enzymes from mushrooms and other sources to detect phenolic compounds more efficiently than traditional methods. The sensors can be made more effective by using tiny materials called nanomaterials, which improve how well they work and how long they last.

The Molecular Mechanism of Polysaccharides from Polygonatum cyrtonema Hua in Improving Hyperuricemia by Regulating Key Targets of Uric Acid Metabolism in Mice

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This research demonstrates that a traditional Chinese medicinal plant called Polygonatum cyrtonema contains beneficial polysaccharides that can help lower high uric acid levels in the blood, which is a major cause of gout and kidney disease. The study found that these polysaccharides work by reducing the enzyme that produces uric acid and helping the kidneys excrete more of it, while also reducing inflammation. Importantly, this natural treatment protected kidney tissue better than the standard pharmaceutical drug allopurinol, suggesting it could be a safer long-term option for managing high uric acid levels.

Disease: Chronic kidney disease