Chronic diseases – mycolab.ai

Modulation of gut microbiome in response to the combination of Escherichia coli Nissle 1917 and sugars: a pilot study using host-free system reflecting impact on interpersonal microbiome

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This study examined how a beneficial bacteria called Escherichia coli Nissle 1917 combined with different types of sugar affects gut bacteria. Researchers found that the effectiveness of these treatments depends heavily on each person’s unique starting microbiota composition, which is shaped by their diet, lifestyle, and health status. The results show that one-size-fits-all probiotic treatments don’t work equally for everyone, and doctors should personalize treatments based on an individual’s existing gut bacteria profile.

Driving Innovation Through Regulatory Design and Corporate Behaviour: A Case Study of Functional Food Industry in Japan

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This study examines how government regulations on health claims for dietary supplements affect how companies in Japan develop and sell these products. The research found that companies willing to invest in their own clinical trials to prove their products work tend to create more successful products and gain bigger market share. The study suggests that well-designed regulations can actually encourage companies to invest more in research and create better, more innovative products rather than just copying existing ones.

Solid-state fermentation as a strategy for improvement of bioactive properties of the plant-based food resources

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This review explains how fermentation—a natural biological process—can enhance the health-promoting compounds in plant-based foods. By using specific fungi and bacteria on solid plant materials, scientists can increase beneficial antioxidants and proteins that may help prevent chronic diseases. This method is more environmentally friendly and cost-effective than traditional extraction techniques, making nutritious plant foods even healthier.

Effect of fiber-modified kombucha tea on gut microbiota in healthy population: A randomized controlled trial (RCT)

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Researchers studied a kombucha tea drink enriched with fiber from chicory root in healthy adults over six weeks. The study found that people who consumed the fiber-enriched kombucha had lower triglyceride levels (blood fats) and beneficial changes in their gut bacteria, particularly an increase in Bifidobacterium, a bacteria known to support digestive health. These results suggest that this type of kombucha could be beneficial for metabolic and gut health, though more research is needed to confirm these benefits.

Metabolomics Profiling of White Button, Crimini, Portabella, Lion’s Mane, Maitake, Oyster, and Shiitake Mushrooms Using Untargeted Metabolomics and Targeted Amino Acid Analysis

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Researchers analyzed seven popular mushroom varieties to understand their chemical makeup. They found over 10,000 different compounds across all mushrooms, with each variety having its own unique set of chemicals. Lion’s mane and oyster mushrooms were particularly rich in L-ergothioneine, a special amino acid thought to have antioxidant and anti-aging properties. The common white button, crimini, and portabella mushrooms had similar nutrient profiles, while specialty mushrooms had distinct chemical signatures.

Harnessing mushrooms for poultry nutrition: Boosting health, immunity, and productivity

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Mushrooms and mushroom stems are emerging as natural feed additives that can significantly improve poultry health, growth, and egg/meat quality while reducing the need for antibiotics. These fungi contain beneficial compounds that boost immune function, reduce harmful bacteria, and protect against cellular damage. By using mushroom byproducts that are typically discarded, farmers can create more sustainable and environmentally friendly poultry production systems while improving overall bird health and productivity.

Probiotic-fortified Solanum lycopersicum (tomato) juice: free or encapsulated Lactobacillus plantarum and Lactobacillus delbrueckii

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This study developed a probiotic-enriched tomato juice using beneficial bacteria wrapped in protective capsules. The encapsulated version maintained better bacterial survival, taste, and health benefits compared to unprotected bacteria during the 28-day storage period. This creates a promising non-dairy functional beverage option for health-conscious consumers seeking improved gut health and antioxidant benefits.

Evaluation of Bioactive Compounds, Antioxidant Activity, and Anticancer Potential of Wild Ganoderma lucidum Extracts from High-Altitude Regions of Nepal

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Researchers studied a medicinal mushroom called Ganoderma lucidum (Reishi) collected from high mountains in Nepal to understand its health benefits. They tested different ways to extract beneficial compounds from the mushroom and found that using ethanol was most effective. The extracts showed strong cancer-fighting properties against cervical cancer cells and powerful antioxidant effects that may help protect the body from damage. These findings suggest this Himalayan mushroom has real therapeutic potential for treating cancer and other diseases.

The Co-Evolution of Markets and Regulation in the Japanese Functional Food Industry: Balancing Risk and Benefit

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This research examines how Japan regulates functional foods – products designed to promote health beyond basic nutrition. The study shows that food regulations have evolved alongside industry growth, trying to balance protecting consumers from unsafe products while allowing companies to innovate and make health claims. Using a framework that examines both safety concerns and consumer benefit information, the authors trace how Japan’s regulatory system changed from the 1960s to today, showing how regulations respond to industry needs and safety incidents.

Mushroom-Based Supplements in Italy: Let’s Open Pandora’s Box

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Researchers tested 19 mushroom supplement products sold in Italy and found serious quality problems. Many supplements didn’t actually contain the mushroom species listed on their labels. Some products also contained toxic substances or inconsistent amounts of beneficial compounds. The study highlights the need for better regulation and manufacturing standards to ensure these popular health products are safe and effective.

Disease: Chronic diseases