Disease: Cervical cancer

Anticancer Activity of Solvent Extracts of Hexogonia glabra against Cervical Cancer Cell Lines

Researchers tested extracts from a wild mushroom species called Hexogonia glabra against cervical cancer cells in the laboratory. The ethanolic extract was most effective, killing cancer cells by triggering apoptosis (programmed cell death) and activating genes that fight cancer. The mushroom extracts showed strong anticancer effects without harming normal cells, suggesting it could be a promising source for developing new cancer drugs.

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Biosynthesis of bimetallic silver–copper oxide nanoparticles using endophytic Clonostachys rosea ZMS36 and their biomedical applications

Scientists discovered a special fungus living inside a medicinal plant that can create tiny silver-copper nanoparticles with powerful antibacterial and anti-cancer properties. These nanoparticles successfully fought dangerous bacteria like MRSA and slowed the growth of cancer cells while being safe to healthy cells. This green manufacturing method is much more environmentally friendly than traditional chemical approaches and could lead to new treatments for infections and cancer.

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Benefits, side effects, and uses of Hericium erinaceus as a supplement: a systematic review

Lion’s Mane mushroom shows promising benefits for brain health, potentially improving memory and reducing symptoms of anxiety and depression. It may help prevent cancer by triggering cancer cell death and supports digestive health by promoting beneficial gut bacteria. While generally safe, some people experience mild side effects like stomach discomfort or headaches, making it an accessible supplement for overall wellness.

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Anticancer Activity of Demethylincisterol A3 and Related Incisterol-Type Fungal Products

This review examines a group of rare fungal compounds called incisterols, with a focus on demethylincisterol A3 (DM-A3), which has shown promise as an anticancer agent. DM-A3 works through multiple mechanisms including blocking cancer cell signaling pathways, inhibiting specific enzymes, and reducing inflammation. The compound has demonstrated effectiveness against various cancer types in laboratory studies and showed tumor-reducing effects in animal models, suggesting potential for future cancer therapy development.

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Mycosynthesis of Metal-Containing Nanoparticles—Synthesis by Ascomycetes and Basidiomycetes and Their Application

Scientists have discovered that common fungi like mushrooms and molds can produce tiny nanoparticles that fight bacteria, kill cancer cells, and speed up chemical reactions. This fungal method is much cheaper, safer, and more environmentally friendly than traditional chemical production methods. The nanoparticles can be used in medical treatments, wound dressings, water purification, and farming as natural fertilizers and pesticides.

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Medicinal Plants for Chemotherapy-Induced Nausea and Vomiting: A Systematic Review of Antiemetic, Chemosensitizing, and Immunomodulatory Mechanisms

This review examines how medicinal plants can help manage nausea and vomiting caused by cancer chemotherapy. Over 22 plants including ginger, cannabis, mint, and turmeric work through multiple mechanisms like blocking serotonin pathways and reducing inflammation. Beyond reducing symptoms, these plants may also enhance chemotherapy effectiveness and boost immune function. The research suggests combining medicinal plants with standard cancer treatments could improve patient outcomes and quality of life.

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Potential of Indonesian Herbal as an Anti-Cancer Therapy: A Systemic Review of in vitro Studies

This review examined eight Indonesian herbal plants that show promise in laboratory studies for fighting various types of cancer. Soursop leaves were the most researched and consistently showed the ability to kill or slow cancer cells in test tubes by triggering natural cell death pathways. The herbs work through bioactive compounds like flavonoids and alkaloids that can interfere with how cancer cells divide and survive. While these results are encouraging, more research is needed to confirm effectiveness in humans.

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Modern Pro-Health Applications of Medicinal Mushrooms: Insights into the Polyporaceae Family, with a Focus on Cerrena unicolor

This review explores how medicinal mushrooms, particularly Cerrena unicolor, can be used to improve health through functional foods and supplements. The mushroom contains natural compounds with powerful properties including fighting cancer cells, killing harmful bacteria and viruses, and protecting the body from oxidative stress. Research shows these mushrooms could be incorporated into dairy products and other foods to create innovative health-promoting products for consumers.

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Mycochemistry, antioxidant activity and anticancer potentiality of ethyl acetate extract of Daldinia eschscholtzii against A549 lung cancer cell line

Researchers studied a wild fungus called Daldinia eschscholtzii to see if it could fight lung cancer. They found that an extract from this fungus contained 28 different beneficial compounds and was effective at killing cancer cells by triggering a process called apoptosis (programmed cell death). The treatment also reduced the cancer cells’ ability to spread, and it appeared safe for normal, healthy cells. Several compounds in the extract showed promise as potential anti-cancer drugs.

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Study on Optimization of Liquid Fermentation Medium and Antitumor Activity of the Mycelium on Phyllopora lonicerae

Scientists optimized how to grow Phylloporia lonicerae fungus in the lab, increasing its production by 142% while cutting growth time by two-thirds. They discovered that certain compounds extracted from this fungus, particularly from a petroleum ether extract, can kill cancer cells and trigger apoptosis. The petroleum ether extract was more effective than the standard cancer drug 5-fluorouracil, especially against esophageal cancer cells, suggesting this fungus could be developed into a natural anti-cancer treatment.

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