Disease: cardiovascular diseases

Evaluation of Lipid Changes During the Drying Process of Cordyceps sinensis by Ultra Performance Liquid Chromatography–Tandem Mass Spectrometry (UPLC-MS/MS)-Based Lipidomics Technique

This study examines how different drying methods affect the lipid content of Cordyceps sinensis, a valuable medicinal mushroom. Researchers compared three drying techniques—freeze-drying, oven-drying, and air-drying—and found that freeze-drying best preserves the mushroom’s beneficial lipids, while oven-drying causes significant degradation. The findings provide practical guidance for mushroom producers on selecting optimal drying methods to maintain the medicinal quality and nutritional value of this prized fungus.

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Screening and characterization of natural extracts as dual-functional regulators for cardiomyocyte regeneration and cardiac repair

Researchers discovered that Ganoderma lucidum water extract can help convert stem cells into heart muscle cells and improve heart function after a heart attack in mice. The extract works by activating a specific cellular pathway called Wnt signaling that is important for heart development. This natural compound shows promise as a dual-action therapy that both regenerates damaged heart tissue and prevents further injury, offering a new approach to treating heart disease using natural products.

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Grape Pomace: A Review of Its Bioactive Phenolic Compounds, Health Benefits, and Applications

Grape pomace is the leftover material from making wine, typically discarded as waste. This review shows that grape pomace is actually packed with beneficial plant compounds called phenolics that have powerful health effects. These compounds can fight bacteria, reduce inflammation, help control blood sugar, and protect heart health, making grape pomace waste valuable for creating new health products in food, cosmetics, and medicine.

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Edible Mushrooms: A Comprehensive Review on Bioactive Compounds with Health Benefits and Processing Aspects

Mushrooms are nutrient-rich foods packed with beneficial compounds that can help prevent various diseases including cancer, heart disease, and diabetes. They contain natural antioxidants and immune-boosting substances that support overall health. Scientists are developing new extraction methods to capture these beneficial compounds more efficiently, and various cooking and processing techniques can help preserve their nutritional value for daily consumption.

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Emerging paradigms for target discovery of traditional medicines: A genome-wide pan-GPCR perspective

Traditional medicines from plants, animals, and fungi contain chemical compounds that can interact with specific proteins in our cells called G protein-coupled receptors (GPCRs). These receptors control many important body functions and are targeted by about one-third of all FDA-approved medications. This review explains how scientists are discovering new therapeutic compounds from traditional medicines by systematically screening them against the complete library of human GPCRs, using advanced techniques to identify which compounds bind to which receptors. Famous examples include morphine from poppies for pain relief and compounds from ginseng that help regulate blood sugar.

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Amylase-assisted extraction alters nutritional and physicochemical properties of polysaccharides and saponins isolated from Ganoderma spp

Researchers studied how enzyme treatment improves extraction of beneficial compounds from reishi mushrooms. They found that using amylase enzyme significantly increased the amounts of healthy polysaccharides and saponins recovered, especially from cultivated black reishi canopies. These extracted compounds work as natural emulsifiers comparable to lecithin and remain stable even at very high temperatures, making them promising ingredients for functional foods and health products.

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Formulation of functional noodles by adding Lentinus edodes mushroom powder: Physiochemical attributes, cellular mineral uptake and improved glycemic index

Researchers developed a healthier version of noodles by adding shiitake mushroom powder at 4% concentration. These mushroom noodles had better nutritional content with more protein and minerals like iron and calcium that the body could actually absorb. Most importantly, the mushroom noodles caused a slower, more gradual rise in blood sugar compared to regular noodles, making them potentially beneficial for people managing diabetes.

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Plant and Fungal Polysaccharides in Periodontitis Treatment: Diverse Mechanisms and Therapeutic Roles

Periodontitis is a serious gum disease that causes tooth loss and affects overall health. This review examines how polysaccharides (complex carbohydrates) from plants and fungi can help treat periodontitis by reducing inflammation, fighting bacteria, and helping gum tissue repair. These natural compounds work through multiple biological pathways to improve oral health outcomes while avoiding the side effects and resistance problems associated with conventional drugs.

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The anti-fatigue and sleep-aiding effects vary significantly among different recipes containing Ganoderma lucidum extracts

Different recipes made from Ganoderma lucidum mushroom have different health benefits. This study tested two recipes in mice and found that one (PGB) was better for reducing fatigue and improving exercise performance, while the other (GBS) was better for improving sleep quality. The research shows that how you prepare and combine medicinal mushroom ingredients matters for what health benefits you get.

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Incorporating Fresh Durum Wheat Semolina Pasta Fortified with Cardoncello (Pleurotus eryngii) Mushroom Powder as a Mediterranean Diet Staple

Researchers created a new type of pasta by mixing regular wheat pasta with powdered Cardoncello mushrooms (Pleurotus eryngii). The mushroom-enriched pasta contains significantly more fiber and antioxidants than regular pasta while maintaining good taste and texture. The product can be labeled as ‘high in fiber’ and shows promise for supporting digestive health through prebiotic effects, making it a healthier option for Mediterranean diet followers.

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