Disease: carcinogenic effects

XenoBug: machine learning-based tool to predict pollutant-degrading enzymes from environmental metagenomes

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XenoBug is a new artificial intelligence tool that helps scientists find bacteria and their enzymes that can break down harmful pollutants like pesticides, plastics, and petroleum products. The tool analyzes genetic information from environmental samples to predict which enzymes can degrade specific toxic chemicals. This discovery approach could make environmental cleanup faster and cheaper by identifying the right microbes for the job. Researchers can use XenoBug to get starting points for developing new biological cleanup solutions.

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Systematic Evaluation of Biodegradation of Azo Dyes by Microorganisms: Efficient Species, Physicochemical Factors, and Enzymatic Systems

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Azo dyes used in textiles and fashion contaminate water supplies and pose health risks including cancer potential. This research review shows that certain microorganisms like specific fungi and bacteria can break down these harmful dyes into less toxic substances through natural enzymatic processes. By optimizing conditions like pH and temperature, and using combinations of different microbes, scientists have achieved degradation rates up to 90%, offering an eco-friendly and cost-effective alternative to traditional chemical treatment methods.

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Bioactive Compounds and Antioxidant Activity of Boletus edulis, Imleria badia, Leccinum scabrum in the Context of Environmental Conditions and Heavy Metals Bioaccumulation

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This study examined three popular edible mushroom species from Poland to understand their nutritional benefits and safety. While all three mushrooms are rich in beneficial compounds like antioxidants and immune-boosting polysaccharides, Boletus edulis (porcini) accumulates concerning levels of cadmium from soil. The research shows these mushrooms are safe in normal amounts, but eating excessive quantities of porcini mushrooms could exceed safe limits for toxic metals, especially for people in polluted areas.

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Nanomaterial-mediated strategies for enhancing bioremediation of polycyclic aromatic hydrocarbons: A systematic review

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This review examines how combining tiny engineered materials (nanomaterials) with natural microorganisms can more effectively clean up environmental pollution from polycyclic aromatic hydrocarbons, which are harmful chemicals produced by burning fossil fuels and other processes. The study found that using nanomaterials alongside bacteria significantly improved pollution removal rates in water and soil, with improvements of up to 19% in liquid samples and 14% in soil samples. Different types of nanomaterials like carbon-based materials and metal oxides work by helping bacteria degrade pollutants more efficiently through various mechanisms. This approach offers a more sustainable and environmentally friendly solution compared to using traditional remediation methods alone.

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Oestrogen Detoxification Ability of White Rot Fungus Trametes hirsuta LE-BIN 072: Exoproteome and Transformation Product Profiling

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A type of white rot fungus called Trametes hirsuta can effectively remove harmful oestrogen chemicals from water and soil. The fungus produces special enzymes that break down these hormones into less toxic compounds within just one day. This discovery suggests the fungus could be used as a natural treatment to clean up environmental contamination caused by oestrogens from human waste and pharmaceutical use.

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Toxic Effects of p-Chloroaniline on Cells of Fungus Isaria fumosorosea SP535 and the Role of Cytochrome P450

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Scientists discovered a fungus called Isaria fumosorosea that can completely break down p-chloroaniline, a toxic chemical used in dyes and pesticides that pollutes our environment. The fungus works by using special enzymes called cytochrome P450 to degrade the pollutant. This discovery could help clean up contaminated soil and water, though more research is needed to ensure it works safely in real-world environments.

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Oestrogen Detoxification Ability of White Rot Fungus Trametes hirsuta LE-BIN 072: Exoproteome and Transformation Product Profiling

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Scientists discovered that a white rot fungus called Trametes hirsuta can effectively remove harmful oestrogen hormones from water and soil. Within just one day, the fungus eliminated more than 90% of two common oestrogens (E1 and E2) that pollute our environment through pharmaceutical waste and animal farming. The fungus achieves this by producing special enzymes that couple oestrogen molecules together into larger, less harmful compounds that can be easily removed.

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