Disease: Carcinogenesis

Cumulative exposure of xenobiotics of emerging concern from agrifood under the One Health approach (XENOBAC4OH)

This research programme examines how harmful chemicals from industry and agriculture accumulate in our food supply and environment. Scientists used a ‘One Health’ approach that considers impacts on humans, animals, and ecosystems together. They tested methods to measure chemical contamination in water and soil, studied how bacteria might break down pollutants, and investigated how different farming practices affect the safety of food crops like tomatoes.

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Pleurotus eryngii Culture Filtrate and Aqueous Extracts Alleviate Aflatoxin B1 Synthesis

This research demonstrates that extracts from oyster mushrooms (Pleurotus eryngii) can effectively prevent the production of aflatoxin B1, a highly toxic and cancer-causing substance produced by certain molds that contaminate crops like corn and wheat. The mushroom extracts work by inhibiting the toxin production by up to 94%, offering a natural, environmentally-friendly alternative to chemical pesticides. The study suggests that compounds in mushrooms, including special sugars and enzymes, may help protect food supplies from this dangerous contamination, which is becoming increasingly important as climate change creates more favorable conditions for mold growth.

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Advances in the Degradation of Polycyclic Aromatic Hydrocarbons by Yeasts: A Review

This review explores how yeasts, tiny single-celled fungi, can clean up environments contaminated with polycyclic aromatic hydrocarbons (PAHs) – harmful chemicals produced by car emissions, factories, and burning. These yeasts use special enzymes to break down these toxic compounds into less harmful substances, making them a promising natural solution for environmental cleanup. Scientists are also improving these yeasts through genetic engineering to make them even more effective at removing pollution.

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Pleurotus eryngii Culture Filtrate and Aqueous Extracts Alleviate Aflatoxin B1 Synthesis

This research demonstrates that extracts from oyster mushrooms (Pleurotus eryngii) can effectively reduce dangerous aflatoxin contamination in food and feed by up to 94%. Aflatoxins are toxic compounds produced by mold fungi that can cause serious health problems including cancer. The study shows that mushroom compounds work through multiple mechanisms including antioxidant activity and enzyme production, offering a natural and environmentally friendly alternative to harmful synthetic chemicals for protecting our food supply.

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