Disease: cancer

A Review of Novel Antioxidant Ergothioneine: Biosynthesis Pathways, Production, Function and Food Applications

Ergothioneine is a powerful natural antioxidant found mainly in mushrooms that protects cells from damage and may help prevent diseases like Alzheimer’s and heart disease. Currently, producing ergothioneine from mushrooms is expensive and slow, but scientists have developed faster fermentation methods using engineered microbes that could make it cheaper and more available. This compound can be added to foods and supplements to boost health benefits, and researchers are exploring its use beyond seafood to other food products like meat and baked goods.

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Environmental Impact of Xenobiotic Aromatic Compounds and Their Biodegradation Potential in Comamonas testosteroni

This review examines how aromatic compounds found in plastics, pesticides, and antibiotics pollute our environment and how bacteria like Comamonas testosteroni can break them down naturally. The research shows that microplastics are accumulating in oceans and wildlife, causing health problems ranging from physical damage to disruption of metabolism and development. Scientists are exploring ways to use these bacteria and microbiome engineering to create biological cleaning systems that could sustainably treat pollution without adding more chemicals to the environment.

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A Comprehensive Review of the Diversity of Fungal Secondary Metabolites and Their Emerging Applications in Healthcare and Environment

Fungi naturally produce complex chemical compounds called secondary metabolites that have powerful effects against diseases and pests. These include well-known medicines like penicillin and compounds that can fight cancer, reduce inflammation, and lower cholesterol. Scientists are now using advanced genetic and biotechnology techniques to increase production of these fungal compounds, making them more available and affordable for medical, agricultural, and environmental applications. This research shows how fungi could be important sources of new medicines and sustainable alternatives to synthetic chemicals.

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Engineering bacterial biocatalysts for the degradation of phthalic acid esters

Phthalic acid esters (PAEs) are chemicals used to make plastics flexible that can leak into the environment and harm human health. Scientists are engineering bacteria with improved enzymes to break down PAEs more efficiently through a process called bioremediation. The review discusses how bacteria naturally degrade these pollutants and outlines strategies to make this process faster and more practical for cleaning contaminated environments.

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High-Yield-Related Genes Participate in Mushroom Production

Scientists have identified specific genes that control how mushrooms grow and produce fruit bodies. By using advanced gene-editing technology like CRISPR-Cas9, researchers can now increase mushroom yields by 20-65%, offering a faster and more efficient alternative to traditional breeding methods. This breakthrough could help meet the world’s growing demand for mushrooms while making farming more sustainable and economical for growers globally.

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Enhancing Pearl oyster mushroom (Pleurotus ostreatus) performance by evaluating the influence of potassium humate and wheat straw on yield and biochemical attributes

This study examined how adding potassium humate (a natural organic compound) to wheat straw substrate affects the growth and quality of oyster mushrooms. Researchers tested seven different amounts of potassium humate over two growing seasons and found that a moderate amount (0.5 g per 500 g straw) produced the best results, increasing both mushroom yield and nutritional value including vitamin C and beneficial sugars. Interestingly, using more potassium humate was not better, showing that balanced application is more effective than maximum supplementation for optimal mushroom production.

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Regulatory effects of Lycium Barbarum polysaccharides on immune function and their application prospects

Lycium barbarum, a plant used in traditional Chinese medicine for over 2000 years, contains special compounds called polysaccharides that boost the immune system. These compounds work by activating immune cells like macrophages and T cells, and can help fight infections and reduce inflammation. Research shows they may also help with conditions like arthritis, cancer, and gut health by acting as a natural prebiotic that promotes beneficial bacteria.

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Deciphering the formation of biogenic nanoparticles and their protein corona: State-of-the-art and analytical challenges

Scientists have developed environmentally friendly methods to create tiny metal particles (nanoparticles) using living organisms like bacteria, fungi, and plants instead of toxic chemicals. These bioengineered nanoparticles are coated with natural biological molecules that make them safer and more stable. This review explains how these particles are made, what analytical tools scientists use to study them, and their potential uses in medicine, environmental cleanup, and agriculture.

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Thin-Layer Chromatography (TLC) in the Screening of Botanicals–Its Versatile Potential and Selected Applications

This review shows how thin-layer chromatography (TLC), a simple laboratory technique, is invaluable for analyzing plant materials. TLC helps scientists identify which plants are related to each other, find beneficial compounds in herbs, ensure herbal medicines are pure and safe, and track illegal psychoactive plants. Despite being less glamorous than modern equipment, TLC remains practical, affordable, and effective for everyday botanical analysis.

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Health benefits of fish and fish by-products—a nutritional and functional perspective

Fish is an excellent food that provides many important nutrients like protein, omega-3 fatty acids, and vitamins that help protect our hearts, brains, and overall health. Different fish species offer various health benefits including protecting against heart disease, diabetes, obesity, and brain disorders. However, some fish can contain harmful contaminants like mercury, so choosing safer options like salmon and cod is important for children and pregnant women.

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