Disease: cancer

Biological Characteristics, Artificial Domestication Conditions Optimization, and Bioactive Components of Beauveria caledonica

Scientists successfully grew Beauveria caledonica mushrooms in a laboratory for the first time using wheat and rice as growing media. They identified the best growing conditions and found that these mushrooms contain beneficial compounds like polysaccharides and adenosine, which may have health benefits similar to traditional medicinal Cordyceps. The adenosine content was significantly higher than what is required by Chinese pharmacopoeia standards, suggesting these cultivated mushrooms could have strong medicinal value.

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Enhancing Nutritional Quality and Functionality of Legumes: Application of Solid-State Fermentation With Pleurotus ostreatus

Researchers used a mushroom fungus (Pleurotus ostreatus) to ferment lentils, chickpeas, and soybeans, making them more nutritious and easier for the body to digest. The fermentation process reduced harmful compounds called antinutrients while boosting protein content and antioxidant power. This simple bioprocessing method could help create healthier plant-based foods that rival animal protein sources in nutritional quality.

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Utilization of Corn Steep Liquor for the Production of Fairy Chemicals by Lepista sordida Mycelia

Researchers found that corn steep liquor, a waste product from corn processing, can be used as an inexpensive ingredient to help grow mushroom mycelia that produce fairy chemicals. Fairy chemicals are special compounds with potential uses in agriculture and cosmetics, but they are very expensive to produce. By using different concentrations of corn steep liquor in growth media, scientists determined optimal conditions for either growing more mycelia or producing more of the beneficial chemicals, making these compounds more affordable for practical use.

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Microbial-Based Green Synthesis of Silver Nanoparticles: A Comparative Review of Bacteria- and Fungi-Mediated Approaches

Scientists have developed environmentally friendly ways to create tiny silver particles using bacteria and fungi instead of harsh chemicals. These silver nanoparticles can fight bacteria, help treat cancer, clean contaminated water, and improve food packaging. The review shows that bacteria produce particles quickly but fungi are better for large-scale production and create more stable particles.

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Multi-omics analysis of Taiwanofungus gaoligongensis: effects of different cultivation methods on secondary metabolites

Scientists studied a medicinal mushroom species to understand how different growing methods affect its beneficial compounds. They found that growing the mushroom on specific wood substrates (from cinnamon trees) produced much higher levels of therapeutic compounds compared to rice-based cultivation. Using advanced molecular techniques, they identified the genes responsible for producing these medicinal compounds and how they are controlled, providing insights to improve mushroom cultivation for better health benefits.

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Influence of Culture Conditions on Bioactive Compounds in Cordyceps militaris: A Comprehensive Review

Cordyceps militaris is a medicinal fungus used traditionally for treating fatigue, boosting immunity, and managing various health conditions. This comprehensive review explains how different growing methods, nutrients, light, temperature, and substrate materials affect the production of beneficial compounds in the fungus. The findings show that mixing grains with insect materials and using specific light conditions can significantly increase production of cordycepin, the most promising compound for cancer and immune health. The review identifies that more standardized growing methods and better understanding of the fungus’s metabolism are needed to make large-scale production practical and affordable.

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Energy Metabolism Enhance Perylenequinone Biosynthesis in Shiraia sp. Slf14 through Promoting Mitochondrial ROS Accumulation

Scientists studied two similar fungi to understand how one produces more of a beneficial compound called perylenequinones (PQs), which have medical uses against infections and cancer. They discovered that the high-producing strain uses energy more efficiently, which causes tiny structures in the cells called mitochondria to produce reactive molecules (ROS). These reactive molecules trigger the fungus to make more PQs as a protective response. By controlling these processes, researchers can potentially improve the production of this valuable medicine.

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Exploring the Critical Environmental Optima and Biotechnological Prospects of Fungal Fruiting Bodies

This research identifies the ideal growing conditions for fungal fruiting bodies like mushrooms, showing that temperature around 25°C, high humidity, and proper light exposure are key factors. The study reveals that exceeding these optimal conditions typically harms development more than staying slightly below them. Scientists discovered that fungal fruiting bodies have important uses in medicine, food production, and environmental cleanup, and new genetic technologies like CRISPR could improve cultivation methods for better yields and quality.

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Addressing Patient Requests to Add Dietary Supplements to Their Cancer Care—A Suggested Approach

Cancer patients often want to use dietary supplements alongside their conventional cancer treatments to manage side effects, boost immunity, and feel more in control of their health. Many patients don’t tell their doctors about supplement use because they worry about judgment or think doctors won’t understand their interests. This paper suggests doctors should have open, non-judgmental conversations with patients about supplements, evaluate their safety and effectiveness using reliable information sources, and work together with patients to make informed decisions that keep them safe while respecting their choices.

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Centesimal Composition, Bioactive Compounds, Antioxidant and α-Glucosidase Inhibitory Activities of Commercial Edible Oyster Mushrooms at Different Maturity Stages in Northern Thailand

This study examined how oyster mushrooms change nutritionally and chemically as they mature from young to fully grown. Researchers found that while mature mushrooms have more overall nutrients and starch-like compounds, younger middle-stage mushrooms have higher levels of beneficial antioxidant compounds and special substances that may help manage blood sugar. The findings suggest that when and how you harvest mushrooms matters for what health benefits they provide, helping farmers and food makers decide when to pick mushrooms based on what they want to produce.

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