breast cancer – Page 5

Unlocking Reishi’s secrets: nutritional and medicinal traits of Ganoderma lucidum isolated from tree bark in Egypt

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Reishi mushrooms (Ganoderma lucidum) from Egypt show promise as natural medicine. Researchers tested extracts and found they can fight bacteria, viruses, and cancer cells in laboratory tests. The mushrooms are rich in beneficial compounds like vitamins and antioxidants. While the extract was not as strong as conventional drugs, it showed good safety profiles and potential for development into new medicines.

Anticancer Activity of Demethylincisterol A3 and Related Incisterol-Type Fungal Products

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This review examines a group of rare fungal compounds called incisterols, with a focus on demethylincisterol A3 (DM-A3), which has shown promise as an anticancer agent. DM-A3 works through multiple mechanisms including blocking cancer cell signaling pathways, inhibiting specific enzymes, and reducing inflammation. The compound has demonstrated effectiveness against various cancer types in laboratory studies and showed tumor-reducing effects in animal models, suggesting potential for future cancer therapy development.

Mycosynthesis of Metal-Containing Nanoparticles—Synthesis by Ascomycetes and Basidiomycetes and Their Application

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Scientists have discovered that common fungi like mushrooms and molds can produce tiny nanoparticles that fight bacteria, kill cancer cells, and speed up chemical reactions. This fungal method is much cheaper, safer, and more environmentally friendly than traditional chemical production methods. The nanoparticles can be used in medical treatments, wound dressings, water purification, and farming as natural fertilizers and pesticides.

Lectins as versatile tools to explore cellular glycosylation

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Lectins are natural proteins that selectively bind to sugars on cell surfaces, discovered over 130 years ago as tools for studying cell chemistry. They have become especially valuable in cancer research, revealing how cancer cells have abnormal sugar patterns that predict how aggressively they spread. Modern biotechnology now allows scientists to create enhanced lectin versions and use them in high-throughput screening to discover new disease markers and improve patient diagnosis.

Anti-Xanthine Oxidase 5′-Hydroxyhericenes A–D from the Edible Mushroom Hericium erinaceus and Structure Revision of 3-[2,3-Dihydroxy-4-(hydroxymethyl)tetrahydrofuran-1-yl]-pyridine-4,5-diol

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Researchers isolated new compounds from Lion’s mane mushroom (Hericium erinaceus) that can inhibit xanthine oxidase, an enzyme linked to breast cancer development. One compound called hericerin showed strong activity against a specific type of breast cancer cell (T47D cells) while being less harmful to normal cells. The study also corrected a misidentification from previous research, confirming that a compound previously thought to have a different structure was actually adenosine. These findings suggest Lion’s mane could be developed into a natural anti-cancer treatment.

Potential of Indonesian Herbal as an Anti-Cancer Therapy: A Systemic Review of in vitro Studies

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This review examined eight Indonesian herbal plants that show promise in laboratory studies for fighting various types of cancer. Soursop leaves were the most researched and consistently showed the ability to kill or slow cancer cells in test tubes by triggering natural cell death pathways. The herbs work through bioactive compounds like flavonoids and alkaloids that can interfere with how cancer cells divide and survive. While these results are encouraging, more research is needed to confirm effectiveness in humans.

Modern Pro-Health Applications of Medicinal Mushrooms: Insights into the Polyporaceae Family, with a Focus on Cerrena unicolor

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This review explores how medicinal mushrooms, particularly Cerrena unicolor, can be used to improve health through functional foods and supplements. The mushroom contains natural compounds with powerful properties including fighting cancer cells, killing harmful bacteria and viruses, and protecting the body from oxidative stress. Research shows these mushrooms could be incorporated into dairy products and other foods to create innovative health-promoting products for consumers.

Mycochemistry, antioxidant activity and anticancer potentiality of ethyl acetate extract of Daldinia eschscholtzii against A549 lung cancer cell line

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Researchers studied a wild fungus called Daldinia eschscholtzii to see if it could fight lung cancer. They found that an extract from this fungus contained 28 different beneficial compounds and was effective at killing cancer cells by triggering a process called apoptosis (programmed cell death). The treatment also reduced the cancer cells’ ability to spread, and it appeared safe for normal, healthy cells. Several compounds in the extract showed promise as potential anti-cancer drugs.

Ganoderma lucidum inspired silver nanoparticles and its biomedical applications with special reference to drug resistant Escherichia coli isolates from CAUTI

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Researchers created tiny silver particles using a medicinal mushroom called Ganoderma lucidum to fight dangerous bacteria that resist antibiotics and are associated with urinary catheter infections. These nanoparticles were found to effectively kill drug-resistant bacteria, work as antioxidants better than a common antioxidant standard, and showed promise in killing breast cancer cells. This eco-friendly approach offers a natural alternative to conventional antibiotics for treating serious antibiotic-resistant infections.

Taxonomic characterization and cytotoxic potential of Vietnamese Ganoderma ellipsoideum against human breast cancer MCF-7 cells

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Scientists discovered a mushroom species called Ganoderma ellipsoideum in Vietnam that shows promise in fighting breast cancer. When tested on cancer cells in the laboratory, extracts from this mushroom killed cancer cells effectively. Computer modeling showed that compounds from this mushroom fit perfectly into and block proteins that help cancer cells grow and spread. This discovery suggests the mushroom could be a natural source for developing new cancer drugs.

Disease: breast cancer