breast cancer – Page 3

The treasured giants: a current overview on agricultural, nutritional, bioactive, and economic potential of Macrocybe Species (Agaricales, Basidiomycota)

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Macrocybe mushrooms are giant edible fungi found in tropical regions worldwide that offer significant nutritional and health benefits. These mushrooms can be cultivated using agricultural waste materials like sawdust and straw, making them an economical crop. Rich in proteins, fibers, vitamins, and medicinal compounds, they possess antimicrobial and immune-boosting properties that could benefit human health.

Immunomodulatory Effects of Edible and Medicinal Mushrooms and Their Bioactive Immunoregulatory Products

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Mushrooms have been used for health for thousands of years and contain special compounds that help boost the immune system and fight cancer. Scientists have identified several key active ingredients in mushrooms like polysaccharides and proteins that can activate immune cells and reduce tumors. Some mushroom products like lentinan from shiitake mushrooms have already been approved as cancer treatments in Japan. While most evidence comes from lab studies, ongoing research suggests mushroom-based medicines could become important therapeutic options.

Research progress of edible mushroom polysaccharide-metal trace element complexes

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This research reviews how edible mushroom polysaccharides can be combined with essential metals like iron, selenium, and zinc to create health-boosting supplements. These complexes improve how our bodies absorb and use these important minerals, offering benefits like better immune function, antioxidant protection, and potential cancer-fighting properties. Scientists are studying different ways to make these complexes and testing their effectiveness for treating various health conditions.

Current Uses of Mushrooms in Cancer Treatment and Their Anticancer Mechanisms

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This comprehensive review examines how medicinal mushrooms can help treat cancer. Certain mushroom species and their compounds, particularly polysaccharides, can boost the immune system to fight cancer cells, reduce chemotherapy side effects, and overcome drug resistance. Multiple mushrooms are currently in clinical trials showing promise in improving cancer patient outcomes when used alongside conventional treatments.

Can Ganoderma Triterpenoids Exert Immunogenic Cell Death in Human Cancer Cells? A Systematic Review and Protein Network Analysis

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This review examines whether compounds from medicinal mushrooms called Ganoderma can help the body’s immune system fight cancer more effectively. Researchers analyzed 69 scientific studies and found that Ganoderma compounds cause cancer cells to die and trigger immune-activating signals. While these results are promising, more experiments are needed to prove whether these mushroom compounds actually activate the specific immune pathways required for long-term cancer control.

Recent Advances in the Use of Ganoderma lucidum and Coriolus versicolor Mushrooms to Enhance the Anticancer Efficacy of EGFR-Targeted Drugs in Lung Cancer

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This review explores how two medicinal mushrooms traditionally used in Asian medicine—Lingzhi and Yunzhi—can enhance the effectiveness of lung cancer drugs (EGFR-TKIs) and help overcome drug resistance. These mushrooms contain special compounds that can fight cancer in multiple ways, boost the immune system, and reduce side effects. The research suggests that combining these mushrooms with standard cancer treatments may improve outcomes for lung cancer patients.

Evaluation of Anticancer Potential of Ganoderma lucidum on MCF-7 Breast Cancer Cells Through Genetic Transcription of Energy Metabolism

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Researchers tested extracts from Ganoderma lucidum (Reishi mushroom) against breast cancer cells in the laboratory. They found that the methanol extract was particularly effective at killing cancer cells while leaving healthy cells relatively unharmed. The mushroom works by disrupting the cancer cells’ metabolism and triggering programmed cell death, making it a promising natural treatment option that could complement conventional cancer therapies.

In vitro antitumor effects of methanolic extracts of three Ganoderma mushrooms

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Researchers tested extracts from three types of medicinal mushrooms (Ganoderma) against cancer cells in laboratory tests. They found that one species was particularly effective against liver cancer cells, while two other species worked well against breast cancer cells. The extracts killed cancer cells while being much less harmful to normal cells, suggesting they could potentially be developed into new cancer treatments.

rFIP-GMI Suppresses IGF-1–Induced Invasion and Migration in Breast Cancer Cells via PI3K/Akt/β-Catenin Inhibition

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Researchers found that a protein from a medicinal mushroom called Ganoderma microsporum can fight aggressive breast cancer by blocking a cellular pathway that helps cancer cells spread. The protein works by stopping the activation of key molecules (PI3K and Akt) that cancer cells use to invade surrounding tissues and migrate to other parts of the body. By blocking this pathway, the mushroom protein also prevents another molecule called β-catenin from entering the cell nucleus, where it would trigger genes that promote cancer growth and spread.

Antioxidant Activity of Mushroom Extracts/Polysaccharides—Their Antiviral Properties and Plausible AntiCOVID-19 Properties

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Mushrooms contain special compounds called polysaccharides that act as natural antioxidants and can fight viruses. These compounds help boost the immune system and reduce inflammation in the body. While mushrooms have shown promise against various viruses including COVID-19, more research is needed to fully develop them as treatments.

Disease: breast cancer