Disease: bloodstream infection

Magnusiomyces capitatus bloodstream infection in a patient with acute monocytic leukemia: A rare case report

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A 26-year-old patient with acute leukemia developed a rare fungal bloodstream infection caused by Magnusiomyces capitatus during cancer treatment. The infection was identified through advanced laboratory techniques including DNA sequencing and mass spectrometry. The patient was successfully treated with amphotericin B, highlighting the importance of rapid and accurate fungal identification for better patient outcomes.

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Caspofungin therapy in prosthetic valve endocarditis and candidemia due to itraconazole-resistant Candida glabrata (Nakaseomyces glabratus): A case report

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A 13-year-old boy developed a serious fungal infection of his heart valve after receiving an artificial valve replacement. The initial antibiotic (itraconazole) did not work because the fungus became resistant, likely by forming a protective biofilm. After identifying the resistant fungus through specialized testing, doctors switched to a different medication called caspofungin. The patient fully recovered with this new treatment and remained healthy during follow-up, showing that combination of precise identification and targeted treatment can overcome antibiotic resistance.

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First report of infections due to Candidozyma (formerly Candida) auris in Botswana, 2022–2024

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Researchers in Botswana discovered the first documented cases of a dangerous fungal infection called Candidozyma auris in their country. This yeast was found in 10 patients at a major hospital, mostly in intensive care units, between 2022 and 2024. The fungus was resistant to common antifungal drugs like fluconazole but could still be treated with other medications. The findings highlight how this emerging pathogen is spreading across Africa and stress the importance of improved laboratory testing and disease monitoring in developing countries.

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