Disease: Binge eating disorder

Exploring the neurobiological correlates of psilocybin-assisted psychotherapy in eating disorders: a review of potential methodologies and implications for the psychedelic study design

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This review examines how psilocybin-assisted therapy might work for eating disorders by looking at various ways to measure changes in the brain. The authors discuss different brain imaging techniques and other tools that scientists could use to understand how psilocybin affects the brains of people with eating disorders. They emphasize that combining multiple measurement approaches provides the best understanding of how this emerging treatment works and can guide future research and clinical applications.

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Psychedelics and the Serotonin Hypothesis of Eating Disorders

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This review explores how psychedelic drugs like psilocybin (found in certain mushrooms) might help treat eating disorders by promoting flexible thinking and breaking rigid eating patterns. The authors summarize evidence from animal studies and early clinical trials showing that psychedelics work differently than traditional antidepressants by triggering brain changes that help people adopt new, healthier behaviors. While results are promising, more research is needed to determine the best doses, patient populations, and long-term safety.

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Why psychedelic-assisted therapy studies in eating disorders risk missing the mark on outcomes: a phenomenological psychopathology perspective

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This scientific commentary examines how research on psychedelic-assisted therapy for eating disorders may be missing important aspects of how people actually experience the treatment. The authors argue that current study methods rely too heavily on questionnaires that don’t capture the full depth of what people experience during psychedelic sessions. They propose using phenomenological approaches—methods that deeply explore lived experience—to better understand which aspects of the psychedelic experience actually lead to recovery from eating disorders.

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Investigating the Potential of Psilocybin for Compulsive Eating in a Rat Model of Binge Eating

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Researchers tested whether psilocybin, a psychedelic compound from magic mushrooms, could help reduce compulsive eating in rats bred to binge eat high-fat, high-sugar foods. Using a fear-conditioning experiment, they found that a single dose of psilocybin did not reduce the rats’ compulsive eating behavior at the dosage tested. However, the treatment may have affected fear-related freezing responses, suggesting psilocybin might influence brain circuits involved in learning and memory.

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Benefits, side effects, and uses of Hericium erinaceus as a supplement: a systematic review

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Lion’s Mane mushroom shows promising benefits for brain health, potentially improving memory and reducing symptoms of anxiety and depression. It may help prevent cancer by triggering cancer cell death and supports digestive health by promoting beneficial gut bacteria. While generally safe, some people experience mild side effects like stomach discomfort or headaches, making it an accessible supplement for overall wellness.

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