Disease: bacterial infections

Mycosynthesis of Metal-Containing Nanoparticles—Synthesis by Ascomycetes and Basidiomycetes and Their Application

Scientists have discovered that common fungi like mushrooms and molds can produce tiny nanoparticles that fight bacteria, kill cancer cells, and speed up chemical reactions. This fungal method is much cheaper, safer, and more environmentally friendly than traditional chemical production methods. The nanoparticles can be used in medical treatments, wound dressings, water purification, and farming as natural fertilizers and pesticides.

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Diversity and bioprospecting activities of endophytic Fungi associated with different Egyptian medicinal plants

Scientists studied fungi that live inside Egyptian medicinal plants and found that one type called Aspergillus terreus produces compounds with powerful healing properties. These compounds can fight harmful bacteria, reduce oxidative damage, and even kill cancer cells while being safe for normal cells. This discovery suggests that fungi living in medicinal plants could be valuable sources of new medicines, offering hope for developing new treatments for infections and cancer.

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Nutritional contents and antimicrobial activity of the culinary-medicinal mushroom Leccinum scabrum

This study examined the health benefits of Leccinum scabrum, a mushroom used both as food and medicine. Researchers tested extracts from this mushroom against harmful bacteria and found they were very effective at stopping bacterial growth. The extracts were created using two different methods and both worked well, suggesting this mushroom could have practical antimicrobial applications.

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Transcriptome and Metabolome Integration Reveals the Impact of Fungal Elicitors on Triterpene Accumulation in Sanghuangporus sanghuang

Researchers studied how special fungal compounds called elicitors can boost the production of healing substances in a medicinal mushroom called Sanghuangporus sanghuang. By analyzing genes and metabolites, they found that adding elicitors increased beneficial compounds like betulinic acid and 2-hydroxyoleanolic acid by up to 114-fold. These findings suggest a practical way to produce more medicinal compounds from this mushroom for health applications.

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Extraction and Identification of the Bioactive Metabolites Produced by Curvularia inaequalis, an Endophytic Fungus Collected in Iran from Echium khuzistanicum Mozaff

Scientists discovered a beneficial fungus living inside the leaves of an Iranian medicinal plant. They isolated three compounds from this fungus, with the main compound showing powerful activity against drug-resistant bacteria and plant-damaging fungi. This discovery suggests that beneficial fungi within plants could be valuable sources for developing new medicines and natural pesticides.

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Fungal-fungal cocultivation alters secondary metabolites of marine fungi mediated by reactive oxygen species (ROS)

Researchers discovered that when two types of ocean fungi grow together, one of them produces a protective chemical called alternariol that can kill bacteria and cancer cells. This happens because the fungi recognize each other as competitors and trigger special stress signals that activate defensive chemical production. Interestingly, fungi from the ocean respond differently than those from land, suggesting they have evolved unique survival strategies for harsh marine environments.

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Marine Fungal Metabolites: A Promising Source for Antibiofilm Compounds

Bacteria can form protective layers called biofilms that resist antibiotics, causing serious infections. Scientists are discovering that fungi living in seaweed and marine environments produce natural compounds that can break down these biofilm barriers. This review shows that marine fungi offer promising new alternatives to combat antibiotic-resistant infections, though more research is needed to fully explore their potential.

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Genome-Mining Based Discovery of Pyrrolomycin K and L from the Termite-Associated Micromonospora sp. RB23

Scientists discovered two new antimicrobial compounds called pyrrolomycins from bacteria living in termites using genome sequencing and chemical analysis. These compounds contain chlorine atoms and are related to known antibiotics. The research shows how the bacteria protects itself from its own antimicrobial compounds through chemical modifications, offering insights into developing new antibiotics.

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Transcriptome and Metabolome Integration Reveals the Impact of Fungal Elicitors on Triterpene Accumulation in Sanghuangporus sanghuang

Scientists studied how a special fungal treatment can boost the production of beneficial compounds in sanghuang mushrooms. Using advanced molecular analysis techniques, they found that the fungal elicitor significantly increased levels of healing compounds called triterpenes. The treated mushrooms produced 114 times more of one specific compound compared to untreated mushrooms. This research shows how we can grow medicinal mushrooms with higher levels of beneficial substances, which could help develop better treatments for various diseases.

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Natural Antimicrobial Compounds as Promising Preservatives: A Look at an Old Problem from New Perspectives

This review examines natural alternatives to synthetic food preservatives, which are increasingly recognized as potentially harmful. Natural antimicrobial compounds from plants, fungi, and other sources can effectively prevent food spoilage and bacterial contamination. New technologies using light and ultrasound can enhance these natural compounds’ effectiveness. While promising, these natural preservatives need more research and regulatory approval before widespread industrial use.

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