bacterial infections – Page 4

Anticancer Activity of Demethylincisterol A3 and Related Incisterol-Type Fungal Products

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This review examines a special group of fungal compounds called incisterols, with focus on demethylincisterol A3 (DM-A3), which shows promise as a cancer-fighting agent. DM-A3 works through multiple mechanisms: it blocks cancer cell growth pathways, inhibits specific cancer-promoting proteins, and has anti-inflammatory effects. The compound has shown strong activity against various cancer types in laboratory and animal studies, making it a candidate for further development as a potential cancer therapy.

Process Optimization for the Bioinspired Synthesis of Gold Nanoparticles Using Cordyceps militaris, Its Characterization, and Assessment of Enhanced Therapeutic Efficacy

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Scientists successfully created tiny gold particles using an edible mushroom called Cordyceps militaris instead of harsh chemicals. These gold nanoparticles are incredibly small (just 7 nanometers) and showed impressive healing potential against bacteria, diabetes-related enzymes, and even cancer cells in lab tests. The method is environmentally friendly, safe, and could lead to new medical treatments.

Time- and temperature-dependent Pentraxin 3 stability in serum and bronchoalveolar lavage fluid samples

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Pentraxin 3 is a protein marker that helps doctors detect serious fungal infections. This study tested how well this marker stays stable in blood and lung fluid samples when stored at different temperatures over long periods. The results show that samples should be kept frozen at −20°C or −80°C to preserve the marker, but samples left at room temperature or warmer are quickly damaged and unreliable for testing.

Impact of Interactions Between Zn(II) and Selenites in an Aquatic Environment on the Accumulation of Se and Zn in a Fungal Cell

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Researchers studied how Shiitake mushrooms accumulate selenium and zinc from growth media, finding that these two elements form chemical complexes that interfere with absorption. When both elements are present together in the culture medium, they bind to each other instead of being taken up by the mushroom cells, reducing the final content of both nutrients. Understanding this interaction is important for developing enhanced mushroom-based dietary supplements containing both selenium and zinc.

Functionalized Micellar Membranes from Medicinal Mushrooms as Promising Self-Growing Bioscaffolds

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Scientists created special membranes from medicinal mushrooms that can help heal wounds and regenerate damaged skin. These membranes are grown naturally in liquid culture and enriched with extract from mango peels to fight bacteria and promote healing. The material is completely natural, biodegradable, and performs better than many conventional wound healing materials, making it an eco-friendly option for medical applications.

Research Progress of Polysaccharide-Gold Nanocomplexes in Drug Delivery

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Scientists are combining polysaccharides (natural compounds found in plants and organisms) with tiny gold particles to create better drug delivery systems. These hybrid nanoparticles can transport medicines directly to cancer cells while reducing side effects and improving treatment effectiveness. The review discusses how these gold-polysaccharide combinations can also fight bacteria and viruses, making them useful for various medical applications beyond cancer therapy.

Harnessing pycnidia-forming fungi for eco-friendly nanoparticle production, applications, and limitations

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Certain fungi called pycnidial fungi can create tiny particles called nanoparticles that are useful in medicine, agriculture, and environmental cleanup. These fungi naturally produce chemicals and enzymes that reduce metal ions into nanoparticles, which have antimicrobial and cancer-fighting properties. While this biological approach is more environmentally friendly than chemical methods, scientists still need to solve challenges like making it work at large scales and ensuring the nanoparticles are safe and stable.

Unlocking Reishi’s secrets: nutritional and medicinal traits of Ganoderma lucidum isolated from tree bark in Egypt

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Reishi mushrooms (Ganoderma lucidum) from Egypt show promise as natural medicine. Researchers tested extracts and found they can fight bacteria, viruses, and cancer cells in laboratory tests. The mushrooms are rich in beneficial compounds like vitamins and antioxidants. While the extract was not as strong as conventional drugs, it showed good safety profiles and potential for development into new medicines.

Survey of clinical microbiology and infectious disease testing capabilities among institutions in Africa

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This study surveyed laboratory facilities across Africa to understand what infectious disease tests are available. Researchers found that basic tests like bacterial identification are common, but advanced tests for viruses (other than HIV) and fungi are less available. The study highlights the need for investment in laboratory infrastructure to improve disease diagnosis and help countries respond to health emergencies.

Progress of Antimicrobial Mechanisms of Stilbenoids

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Stilbenoids are natural compounds found in plants that can fight harmful bacteria and fungi in multiple ways. Unlike traditional antibiotics that only kill microbes, stilbenoids can also prevent infections by disrupting biofilm formation and weakening pathogen virulence. These compounds show promise in combating drug-resistant infections without promoting further resistance development, making them valuable candidates for new antibiotic medicines.

Disease: bacterial infections