Disease: atherosclerosis

Lysergic Acid Diethylamide (LSD) and the Heart: Exploring the Potential Impacts of LSD on Cardiovascular Function

This review examines how LSD affects the heart and blood vessels. While some evidence suggests LSD might protect against heart disease by reducing inflammation and blood clots, acute use can dangerously raise heart rate and blood pressure, and cause blood vessel constriction. Regular low-dose use raises concerns about potential valve damage. More research is needed to understand the full cardiovascular safety of LSD before it can be considered for medical use.

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How Do Cyclodextrins and Dextrans Affect the Gut Microbiome? Review of Prebiotic Activity

Cyclodextrins and dextrans are substances commonly used in medicines that may have unexpected health benefits for your gut bacteria. Research shows these compounds can help beneficial bacteria like Lactobacillus and Bifidobacterium grow better in your digestive system. When these good bacteria ferment these substances, they produce helpful compounds called short-chain fatty acids that improve overall gut health and may help with conditions like obesity and inflammation.

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Role of Genetically Modified Microorganisms for Effective Elimination of Heavy Metals

Heavy metals like lead, mercury, and arsenic are dangerous pollutants that accumulate in our environment and food chain, causing serious health problems. Traditional methods to remove these metals are expensive and inefficient. Scientists have created genetically modified bacteria and fungi that are much better at absorbing and breaking down heavy metals from contaminated water and soil, offering a cheaper and more environmentally friendly solution to clean up pollution.

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Special Issue: Marine-Derived Compounds Applied in Cardiovascular Disease

This collection of studies explores how compounds from ocean sources like seaweed, fish, shrimp, and microalgae can help protect heart health and prevent cardiovascular diseases. Researchers examined various marine ingredients and found they can reduce inflammation, lower cholesterol, reduce blood pressure, and prevent blood clots. The findings suggest that marine-derived products could become safer, more affordable alternatives or complements to current heart disease medications while supporting sustainable ocean resource use.

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Medicinal Mushrooms as Multicomponent Mixtures—Demonstrated with the Example of Lentinula edodes

Shiitake mushrooms are more than just tasty food—they contain numerous compounds that work together to improve health. Unlike single isolated drugs, whole mushroom preparations offer multiple benefits including boosting immunity, protecting the heart, and potentially supporting cancer treatment. These mushrooms have been used safely in Asian medicine for over 2000 years and are becoming recognized worldwide for their health-promoting properties.

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The Role of Wolfiporia cocos (F. A. Wolf) Ryvarden and Gilb. Polysaccharides in Regulating the Gut Microbiota and Its Health Benefits

Wolfiporia cocos, a fungus used in traditional Chinese medicine for over 2000 years, contains polysaccharides that act as prebiotics to improve gut health. These polysaccharides promote the growth of beneficial bacteria while inhibiting harmful ones, increase production of healthy metabolites, and strengthen the intestinal barrier. By improving gut microbiota composition, these polysaccharides can help prevent and treat various diseases including obesity, diabetes, and inflammatory conditions.

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Bioactive Metabolites from the Fruiting Body and Mycelia of Newly-Isolated Oyster Mushroom and Their Effect on Smooth Muscle Contractile Activity

Researchers isolated a new oyster mushroom strain and studied how it affects digestive system health. They compared the fruiting body and mycelium (root-like structure) and found that water extracts of the fruiting body were rich in beneficial compounds like β-glucans and antioxidants. When tested on stomach muscle tissue, these extracts caused muscle contractions in a dose-dependent manner, suggesting potential benefits for digestive function. This discovery could lead to new natural supplements supporting gut health.

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Screening and characterization of natural extracts as dual-functional regulators for cardiomyocyte regeneration and cardiac repair

Researchers discovered that Ganoderma lucidum water extract can help convert stem cells into heart muscle cells and improve heart function after a heart attack in mice. The extract works by activating a specific cellular pathway called Wnt signaling that is important for heart development. This natural compound shows promise as a dual-action therapy that both regenerates damaged heart tissue and prevents further injury, offering a new approach to treating heart disease using natural products.

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Nettle (Urtica cannabina L.) polysaccharides as a novel dietary supplement: enhancing systemic antioxidant status via modulation of the gut–liver axis

This study found that nettle polysaccharides, especially at lower doses, act as a natural supplement that boosts the body’s antioxidant defenses. The supplement works by promoting beneficial bacteria in the gut, which produce helpful metabolites that signal to the liver to enhance protective antioxidant enzymes. These findings suggest nettle polysaccharides could be a promising natural ingredient for health-conscious food products aimed at maintaining metabolic wellness.

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Modulating the gut microbiota is involved in the effect of low-molecular-weight Glycyrrhiza polysaccharide on immune function

Researchers studied a natural compound from licorice called Glycyrrhiza polysaccharide (GP) to see if it could help restore immune function in mice weakened by chemotherapy. GP treatment improved intestinal health, boosted immune cells, and changed the gut bacteria composition to favor beneficial strains. The study shows that GP works partly by modifying which bacteria live in the gut, which then support the immune system. This research suggests GP could be useful as a natural supplement for strengthening immunity and treating intestinal inflammation.

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