Disease: anaplastic large cell lymphoma

AlkTango reveals a role for Jeb/Alk signaling in the Drosophila heart

Researchers developed a new method to track when and where a specific signaling protein called Alk is active in fruit fly hearts. They discovered that Alk is switched on in heart muscle cells of developing and adult flies, with a nearby protein called Jeb acting as the activating signal. When they increased Alk signaling artificially, flies developed irregular heartbeats and had shorter lifespans, especially under heat stress, revealing an important role for this protein in maintaining healthy heart function.

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Recent Discoveries on Marine Organism Immunomodulatory Activities

Scientists are discovering that creatures from the ocean produce powerful substances that can help our immune system fight diseases like cancer and inflammation. These marine organisms—from tiny algae to sponges to fish—create natural compounds that can either boost or calm down our immune response depending on what we need. Several of these ocean-derived medicines are already approved for treating serious diseases, and many more are being tested in clinical trials. The ocean covers 70% of our planet and most of it remains unexplored, suggesting there are many more beneficial compounds waiting to be discovered.

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