Disease: Alzheimer's disease

Health benefits of fish and fish by-products—a nutritional and functional perspective

Fish is an excellent food that provides many important nutrients like protein, omega-3 fatty acids, and vitamins that help protect our hearts, brains, and overall health. Different fish species offer various health benefits including protecting against heart disease, diabetes, obesity, and brain disorders. However, some fish can contain harmful contaminants like mercury, so choosing safer options like salmon and cod is important for children and pregnant women.

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Psychedelics: Alternative and Potential Therapeutic Options for Treating Mood and Anxiety Disorders

This comprehensive review explores how psychedelic drugs like psilocybin mushrooms, DMT, and LSD may offer new hope for treating depression, anxiety, and PTSD, especially for patients who don’t respond to conventional antidepressants. Historically used in spiritual ceremonies for thousands of years, these compounds are now being scientifically studied and show promise with fewer side effects than many traditional psychiatric medications. The authors emphasize that while results are encouraging, more research and regulatory approval are needed before these treatments become widely available in mainstream medicine.

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Medicinal Mushrooms: Their Bioactive Components, Nutritional Value and Application in Functional Food Production—A Review

Medicinal mushrooms like Reishi, Lion’s Mane, and Shiitake contain powerful compounds that may help fight cancer, boost immunity, and reduce inflammation. These mushrooms are low in calories and can be added to everyday foods like bread, pasta, and meat products to boost their nutritional value. While promising, more research is needed to confirm how much people should consume and whether they interact safely with medications.

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Investigating the Neuroprotective, Hepatoprotective, and Antimicrobial Effects of Mushroom Extracts

This study examined four types of edible mushrooms to see if they could protect against aging and fight harmful bacteria. Researchers gave mice an aging-inducing substance and then treated them with mushroom extracts. The mushrooms, particularly Lion’s Mane (Hericium erinaceus), helped prevent brain and liver damage, reduced inflammation, and showed antibacterial effects against multiple bacterial strains. These findings suggest mushrooms could be useful natural supplements to promote health and combat age-related decline.

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The Acute and Chronic Effects of Lion’s Mane Mushroom Supplementation on Cognitive Function, Stress and Mood in Young Adults: A Double-Blind, Parallel Groups, Pilot Study

This study examined whether Lion’s mane mushroom supplements could improve thinking speed and reduce stress in healthy young adults. Researchers found that a single dose improved how quickly people completed a mental challenge, and four weeks of daily supplements showed a trend toward reducing subjective stress. However, the study was small and found mixed results, including some negative effects on memory tasks, so more research with larger groups is needed to confirm these findings.

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A comprehensive overview of the effects of probiotics, prebiotics and synbiotics on the gut-brain axis

This comprehensive review examines how probiotics (beneficial live bacteria), prebiotics (food for beneficial bacteria), and synbiotics (combinations of both) can influence communication between the gut and brain. These interventions can produce beneficial compounds like GABA and serotonin, strengthen the gut barrier, and reduce inflammation, potentially helping with mood, anxiety, cognition, and various digestive disorders. However, effects vary greatly depending on the specific strain used, dosage, and individual differences in gut bacteria, and more large-scale studies are needed to confirm long-term clinical benefits.

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Neuroprotective Effect of Mixed Mushroom Mycelia Extract on Neurotoxicity and Neuroinflammation via Regulation of ROS-Induced Oxidative Stress in PC12 and BV2 Cells

A mixture of three medicinal mushrooms (Phellinus linteus, Ganoderma lucidum, and Inonotus obliquus) was tested for its ability to protect nerve cells from damage. The extract successfully reduced cell death in laboratory models of neurodegeneration by reducing harmful molecules called reactive oxygen species and reducing inflammation. These results suggest the mushroom extract could potentially help prevent or slow neurological diseases like Alzheimer’s.

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Nature’s Own Pharmacy: Mushroom-Based Chemical Scaffolds and Their Therapeutic Implications

This comprehensive review explores how mushrooms can be used as natural medicines. Various mushroom species contain powerful compounds that can fight cancer, boost immunity, reduce inflammation, and treat infections. The paper details 15 important medicinal mushrooms and their therapeutic uses, showing that mushrooms are indeed a nature’s pharmacy with significant potential for treating many diseases.

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Nanoencapsulation of Biotics: Feasibility to Enhance Stability and Delivery for Improved Gut Health

This review explores how tiny nanoparticles can protect beneficial bacteria and dietary compounds as they travel through the digestive system. These nanotechnologies help probiotics survive stomach acid and reach the intestines where they provide health benefits. The research shows promising results for treating digestive diseases and improving overall gut health through better delivery of microbiota-modulating substances.

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Recent advances and role of melatonin in post-harvest quality preservation of shiitake (Lentinula edodes)

Shiitake mushrooms are nutritious but spoil quickly after harvest due to their high water content and lack of protective skin. This review explores how melatonin and various preservation methods like proper cooling, special packaging, and drying can extend shelf life and maintain quality. Different techniques work by controlling moisture, slowing respiration, preventing browning, and controlling microbial growth. Combining multiple methods, such as vacuum cooling with special packaging, provides the best results for preserving the mushrooms’ taste, nutrition, and appearance.

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