Alzheimer’s disease – Page 2

Scrutinizing the Nutritional Aspects of Asian Mushrooms, Its Commercialization and Scope for Value-Added Products

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Mushrooms are nutrient-dense foods that can help address malnutrition and provide health benefits comparable to meat and eggs. They contain proteins, vitamins, minerals, and special compounds that help fight inflammation, boost immunity, and prevent diseases like cancer and heart disease. Mushroom-based products like powders, capsules, and fortified foods are becoming increasingly available in markets, offering practical ways to incorporate these nutritional benefits into daily diets.

Domestication Cultivation and Nutritional Analysis of Hericium coralloides

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Researchers successfully grew a rare medicinal mushroom called Hericium coralloides from a wild sample found on the Tibetan Plateau. The mushroom is nutrient-rich, containing good amounts of protein and fiber while being low in fat, making it a healthy food choice. The mushroom’s compounds showed strong antioxidant properties and the ability to slow the growth of certain cancer cells, particularly breast cancer cells, suggesting potential health benefits.

Fractionation of Saffron (Crocus sativus L.) Extract by Solid-Phase Extraction and Subsequent Encapsulation in Liposomes Prepared by Reverse-Phase Evaporation

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Saffron is a valuable spice with powerful health benefits, but its beneficial compounds break down easily and don’t absorb well when eaten. This research developed a special two-step process to extract and purify saffron’s active ingredients, then encapsulated them in tiny fatty spheres called liposomes to protect them in the stomach and improve absorption. The results show that liposomes can effectively trap the beneficial saffron compounds, making them more stable and more likely to reach the tissues where they’re needed.

Algal pigments: Therapeutic potential and food applications

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Colorful algae contain powerful natural compounds that can help treat serious health problems like cancer, diabetes, and obesity. Scientists are using special nano-technology to deliver these algal compounds more effectively in medicines. Algae-based pigments like chlorophyll and carotenoids are already used in supplements and healthy foods to boost overall wellness. These compounds also help maintain a healthy gut and reduce inflammation in the body.

Edible mushrooms as emerging biofactories for natural therapeutics and oral biopharmaceutical delivery

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Mushrooms are emerging as natural medicine factories that can be genetically engineered to produce medications taken by mouth. Beyond their traditional use as health foods, scientists are now using advanced genetic techniques to program mushrooms to manufacture therapeutic proteins and vaccines. These engineered mushrooms can naturally package and protect these medications as they pass through the stomach, releasing them safely in the intestines for absorption. This approach offers a sustainable, affordable, and cold-chain-independent alternative to conventional injected medications.

Psychotomimetic compensation versus sensitization

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This paper proposes a new way to understand why drugs that can cause psychosis-like effects (such as psilocybin, LSD, and ketamine) can also help treat depression and anxiety. The authors suggest that these drugs trigger compensatory responses in the brain that temporarily help us cope with stress, similar to how a runner’s high feels good during exercise. However, if someone uses these drugs repeatedly or experiences chronic stress, they may become sensitized and more vulnerable to developing actual psychotic symptoms over time.

A Review of Novel Antioxidant Ergothioneine: Biosynthesis Pathways, Production, Function and Food Applications

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Ergothioneine is a powerful natural antioxidant found mainly in mushrooms that protects cells from damage and may help prevent diseases like Alzheimer’s and heart disease. Currently, producing ergothioneine from mushrooms is expensive and slow, but scientists have developed faster fermentation methods using engineered microbes that could make it cheaper and more available. This compound can be added to foods and supplements to boost health benefits, and researchers are exploring its use beyond seafood to other food products like meat and baked goods.

Impact of Hericium erinaceus and Ganoderma lucidum metabolites on AhR activation in neuronal HT-22 cells

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This study examined how two medicinal mushrooms, lion’s mane and Reishi, affect nerve cells in the brain. The researchers found that metabolites from these mushrooms don’t harm brain cells and actually boost protective proteins that support cell health and survival. The mushrooms appear to work through a cellular receptor called AhR, which helps facilitate communication between the gut and the brain. These findings suggest that these mushrooms may help support brain function and protect against neurological problems.

Thin-Layer Chromatography (TLC) in the Screening of Botanicals–Its Versatile Potential and Selected Applications

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This review shows how thin-layer chromatography (TLC), a simple laboratory technique, is invaluable for analyzing plant materials. TLC helps scientists identify which plants are related to each other, find beneficial compounds in herbs, ensure herbal medicines are pure and safe, and track illegal psychoactive plants. Despite being less glamorous than modern equipment, TLC remains practical, affordable, and effective for everyday botanical analysis.

Bioactive Peptides from Quinoa (Chenopodium quinoa Willd.) as Modulators of the Gut Microbiome: A Scoping Review of Preclinical Evidence

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This review examines how quinoa and its protein-derived peptides can improve gut health by changing the balance of bacteria in the digestive system. Research shows that quinoa helps boost beneficial bacteria, increases diversity of microbial communities, and promotes production of butyrate, a beneficial compound that supports intestinal health. Different disease conditions show specific improvements, such as reduced harmful bacteria in colitis and better metabolic balance in obesity, suggesting quinoa could be tailored for personalized health interventions.

Disease: Alzheimer's disease