Bioactive Compound: Secondary metabolites

Trichoderma and its role in biological control of plant fungal and nematode disease

Trichoderma is a beneficial fungus that can protect crops from diseases and pests while promoting healthier plant growth, without harmful chemical pesticides. It works through multiple strategies: competing with harmful fungi for nutrients, producing natural toxins that kill pathogens, directly parasitizing disease-causing organisms, and strengthening the plant’s own immune system. This eco-friendly approach reduces chemical pollution while improving crop quality and yields, making it an ideal solution for sustainable farming.

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The phenomenon of strain degeneration in biotechnologically relevant fungi

Fungi used in industries to produce antibiotics, enzymes, and other useful products sometimes mysteriously lose their ability to produce these substances effectively. This review explains why this happens through various mechanisms including genetic changes, chemical modifications of genes, and stress responses. The authors provide practical strategies to prevent this loss of productivity, such as careful strain selection, proper storage methods, and tailored bioprocess design to maintain stable production.

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