Anti-Therapeutic Action: toxicity concerns

Drug repurposing to fight resistant fungal species: Recent developments as novel therapeutic strategies

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Fungal infections are becoming increasingly difficult to treat due to growing drug resistance, affecting millions of people worldwide each year. This research collection explores creative solutions by repurposing existing medications and developing new combination therapies that work better together against resistant fungal species. Studies show promising results combining common antibiotics like minocycline with antifungal drugs, and natural compounds from traditional medicine show potential for treating hard-to-treat infections like Candida and Aspergillus.

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Drug repurposing to fight resistant fungal species: Recent developments as novel therapeutic strategies

mycolabadmin

This editorial highlights the growing problem of fungal infections that resist current treatments, causing millions of deaths worldwide each year. Researchers are finding new ways to fight these resistant infections by repurposing existing drugs in new combinations and discovering novel compounds from natural sources. The collection of studies presented shows promising results using combinations like minocycline with antifungal drugs, natural compounds like baicalin, and AI technology to predict resistance patterns. These innovative approaches offer hope for better treatment options for patients suffering from serious fungal infections.

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The ethnomycological knowledge of Karajá indigenous people from Bananal Island, Brazil

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Researchers studied how the Karajá indigenous people of Brazil understand and use fungi in their daily lives. While the Karajá don’t eat mushrooms as food, they recognize various fungi in their environment and use them for medicine, decorations in festivals, and childhood play. The study found that the Karajá have a neutral to slightly positive view of fungi, neither strongly liking nor disliking them, and their knowledge is passed down through families from childhood.

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