Anti-Therapeutic Action: Toxicity

“Plants of the Gods” and their hallucinogenic powers in neuropharmacology — A review of two books

mycolabadmin

This review examines two books about plants that have been used in religious and healing rituals across many cultures for their mind-altering properties. The author verifies that the hallucinogenic plants described in Carlos Castaneda’s popular books about a Yaqui sorcerer are accurately portrayed pharmacologically. The review explains how different sacred plants like peyote, certain mushrooms, and nightshade varieties affect the brain through various chemical pathways, while noting their dangers when misused.

Read More »

Mushroom data creation, curation, and simulation to support classification tasks

mycolabadmin

This study creates a new dataset of over 61,000 mushroom records from 173 species to help computers learn to identify whether mushrooms are safe to eat or poisonous. The researchers extracted mushroom information from an identification textbook and used computer programs to generate realistic hypothetical mushroom entries. They tested different AI methods and found that random forests (a type of machine learning algorithm) worked best, achieving perfect accuracy in identifying poisonous versus edible mushrooms.

Read More »

Diverse origins of fibrinolytic enzymes: A comprehensive review

mycolabadmin

Blood clots can cause heart attacks and strokes, which are major causes of death worldwide. Currently used clot-dissolving drugs have significant drawbacks including short effectiveness periods and side effects. This review examines how fibrinolytic enzymes—naturally occurring proteins that dissolve blood clots—can be obtained from various sources, especially fermented foods like Japanese natto. These enzymes show promise as safer, cheaper alternatives that could be produced in large quantities for treating cardiovascular diseases.

Read More »

Past, present and future of antifungals: Advancements in mechanisms of action and resistance

mycolabadmin

Fungal infections are a growing global health threat, especially for people with weakened immune systems, causing millions of deaths annually. Currently available antifungal drugs are limited and increasingly face resistance, making them less effective over time. This special collection of research papers explores new approaches to treating fungal infections, including novel drugs, combination therapies, and alternative treatments to overcome resistance. Scientists and doctors hope these advances will help save more lives by providing better options for treating serious fungal diseases.

Read More »

A novel pan-fungal screening platform for antifungal drug discovery: proof of principle study

mycolabadmin

Researchers developed a faster, more efficient screening method to test potential antifungal drugs against multiple disease-causing fungi simultaneously. Using an improved growth medium and screening 500 chemical fragments, they identified compounds with antifungal activity and demonstrated the platform can reliably detect promising drug candidates. This approach could accelerate the discovery of new antifungal medications, which are urgently needed as fungi develop resistance to current treatments.

Read More »
Scroll to Top