Anti-Therapeutic Action: Tissue invasion

Bacterial–Fungal Interactions: Mutualism, Antagonism, and Competition

Bacteria and fungi in animal bodies interact in three main ways: they help each other (mutualism), fight each other (antagonism), or compete for resources. These interactions happen in the gut, rumen, and skin of animals. Understanding how to balance these relationships can help create better probiotics and natural alternatives to antibiotics for treating infections and improving animal health.

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Candida albicans Goliath cells pioneer biofilm formation

When Candida albicans fungi run out of zinc, they transform into larger cells called ‘Goliath cells’ that are exceptionally sticky to plastic surfaces. Scientists found that these Goliath cells are much better at sticking to catheters and other medical devices than regular yeast cells, even when blood is flowing past them. This discovery helps explain why fungal infections on catheters are so common and could lead to better ways to prevent these dangerous infections that affect hospitalized patients.

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Schizophyllum commune

Schizophyllum commune, commonly known as the split-gill mushroom, is a fungus that grows on wood and was historically considered just a common environmental organism. However, scientists discovered in 1950 that this mushroom could actually infect human tissue, causing conditions like nail infections. This discovery was surprising because mushrooms were not previously known to infect living animals. Today, researchers recognize it as an emerging fungal pathogen that can pose health risks to humans.

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