Anti-Therapeutic Action: tissue destruction

Stonebrood Disease—Histomorphological Changes in Honey Bee Larvae (Apis mellifera) Experimentally Infected with Aspergillus flavus

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Stonebrood is a rare fungal disease of honey bees caused by Aspergillus flavus that can kill bee larvae very quickly. Researchers experimentally infected bee larvae with the fungus and tracked how the disease progressed, finding that larvae died within 48 hours of infection. The study revealed that the fungus likely kills bees by producing toxins rather than by physical damage, and poses a health risk to beekeepers who inhale the fungal spores.

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Chalkbrood Disease Caused by Ascosphaera apis in Honey Bees (Apis mellifera)—Morphological and Histological Changes in Infected Larvae

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Chalkbrood is a serious fungal disease that kills honeybee larvae, caused by the fungus Ascosphaera apis. This study examined exactly how the infection progresses by infecting larvae in controlled laboratory conditions and observing them over time under a microscope. The researchers found that once infected, larvae die very quickly within 3-7 days as the fungus spreads throughout their bodies, and the fungus continues to grow even after the larvae are dead, eventually forming visible spores on the dead larvae that spread the disease to other bees in the colony.

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Stonebrood Disease—Histomorphological Changes in Honey Bee Larvae (Apis mellifera) Experimentally Infected with Aspergillus flavus

mycolabadmin

Researchers studied how a rare fungal disease called stonebrood affects honey bee larvae by infecting them with the fungus Aspergillus flavus. They found that the fungus establishes in the bee’s gut within 24 hours and kills the larvae within two days, likely through production of toxic compounds. The study reveals three stages of infection progression and highlights why beekeepers need protection when handling infected colonies.

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