Anti-Therapeutic Action: strain degeneration reduces antioxidant capacity and flavonoid production

Integrated Transcriptomics and Metabolomics Provide Insight into Degeneration-Related Molecular Mechanisms of Morchella importuna During Repeated Subculturing

This study explains why morel mushroom strains weaken when repeatedly grown in laboratories. Researchers found that degenerated strains lose the ability to produce protective compounds called flavonoids, which act as natural antioxidants. By understanding these molecular changes, the researchers suggest that avoiding frequent subculturing and using preservation methods like low-temperature storage could help keep morel strains healthy and productive.

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