Anti-Therapeutic Action: Resistance to voriconazole

First human case of Eidernor doerrieniae colonization in a peritoneal dialysis catheter: A warning from silent contamination

A 52-year-old dialysis patient noticed brownish particles inside his peritoneal dialysis catheter. Doctors identified a rare fungus called Eidernor doerrieniae using DNA sequencing, which had never been found in humans before. The catheter was removed and the patient received antifungal medications that successfully eliminated the infection without causing serious complications.

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First human case of Eidernor doerrieniae colonization in a peritoneal dialysis catheter: A warning from silent contamination

A 52-year-old man on peritoneal dialysis noticed brownish particles in his dialysis catheter. Doctors identified the particles as a rare fungus called Eidernor doerrieniae, which had never been found in humans before. Although the patient had no symptoms, doctors immediately removed the catheter and treated him with antifungal medications, which successfully cured the infection. This case shows why patients and doctors should take visible particles in dialysis catheters seriously, even when there are no obvious signs of infection.

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Mucor germinans, a novel dimorphic species resembling Paracoccidioides in a clinical sample: questions on ecological strategy

Researchers discovered a new fungus called Mucor germinans that infected a cancer patient’s lungs and appeared as yeast cells rather than the typical thread-like fungal structures. This is unusual because Mucor infections normally show filamentous hyphae, and the yeast-like appearance made it look like a different fungus, potentially delaying correct diagnosis and treatment. The study shows that this fungus can change forms depending on temperature and other conditions, and identifying it requires checking for multiple nuclei in the cells to distinguish it from other similar-looking yeasts.

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Mucor germinans, a novel dimorphic species resembling Paracoccidioides in a clinical sample: questions on ecological strategy

Researchers identified a new fungal species called Mucor germinans from a patient with Burkitt lymphoma that can switch between filamentous and yeast-like forms. This is unusual because Mucor species are typically identified by their thread-like filaments, not budding yeast cells. The yeast form appeared at body temperature and resembled a different fungus called Paracoccidioides, potentially causing misdiagnosis. The discovery emphasizes the importance of recognizing that some Mucor infections may present with yeast-like cells and highlights the need for rapid, accurate identification to guide appropriate antifungal treatment.

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