Anti-Therapeutic Action: potential effects on non-target organisms

Antifungal mechanism of ketone volatile organic compounds against Pseudogymnoascus destructans

Researchers discovered that two ketone compounds, 2-undecanone and 2-nonanone, effectively kill Pseudogymnoascus destructans, the fungus that causes white-nose syndrome in bats. Using advanced genetic analysis, they found these ketones work by damaging the fungus’s cell structure, disrupting its energy production, and causing DNA damage. This research provides a foundation for developing new fumigant treatments to protect bat populations from this devastating fungal disease.

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