Not mentioned – Page 2

Classification of polyphenol oxidases shows ancient gene duplication leading to two distinct enzyme types

mycolabadmin

Scientists performed a comprehensive study organizing thousands of similar enzymes called polyphenol oxidases (PPOs) found across all living organisms into 12 distinct groups based on their evolutionary relationships. They discovered that a major gene duplication event in ancient times created two main types of these enzymes with different structural features and functions. This new classification system shows that fungal enzymes called o-methoxy phenolases are particularly abundant in certain fungi, likely helping them break down plant materials like lignin.

Morphological and molecular development of Terfezia claveryi ectendomycorrhizae exhibits three well-defined stages

mycolabadmin

This study tracked how desert truffles form a beneficial partnership with plant roots over 10 weeks, identifying three distinct stages with different structures and genetic activity patterns. Researchers used microscopy and gene analysis to understand how the fungus gradually colonizes the root system, starting with growth in soil, then spreading between root cells, and finally penetrating inside cells. The findings reveal that specific fungal and plant genes are active at different stages, particularly those involved in breaking down plant cell walls. This research helps explain how desert truffles can be cultivated more effectively for food production.

Evidence for the Existence of Mating Subtypes Within the Schizophyllum commune: Mating Behavior and Genetic Divergence

mycolabadmin

Researchers discovered that a common fungus called Schizophyllum commune has hidden genetic subtypes within its mating types that weren’t recognized before. By studying 149 fungal strains and analyzing their mating behavior, they found that fungi with the same mating type could still behave differently when reproducing. Specific genes controlling pheromone chemicals were identified as responsible for these differences, revealing more complexity in fungal reproduction than previously understood.

Polysaccharide prediction in Ganoderma lucidum fruiting body by hyperspectral imaging

mycolabadmin

Researchers developed a quick, damage-free method to measure the health-promoting polysaccharide content in Ganoderma lucidum mushrooms using special imaging technology that analyzes light reflection. This technology combines visible and near-infrared light imaging with computer learning to predict polysaccharide levels across the entire mushroom cap. The method achieved 92.4% accuracy and could help mushroom farmers determine the best time to harvest for maximum nutritional value.

Astragalus Shiitake—A Novel Functional Food with High Polysaccharide Content and Anti-Proliferative Activity in a Colorectal Carcinoma Cell Line

mycolabadmin

Scientists developed a new type of Shiitake mushroom by growing it on a special substrate enriched with Astragalus root. This novel mushroom contains significantly more beneficial polysaccharides than regular Shiitake. When tested against colorectal cancer cells, extracts from this mushroom showed strong cancer-fighting properties, with the ultrasound extraction method being most effective. This research suggests Astragalus Shiitake could become a powerful functional food for cancer prevention and treatment.

Research advances in fungal polysaccharides: production, extraction, characterization, properties, and their multifaceted applications

mycolabadmin

This comprehensive review examines fungal polysaccharides, which are complex sugar molecules found in mushrooms and fungi that have powerful health benefits. Researchers describe how to grow and extract these compounds from various fungi, and explain their uses in treating diseases like cancer, reducing inflammation, and boosting immunity. The review covers different growing and extraction methods used worldwide and discusses future directions for using these natural compounds in medicine and industry.

Quest for Anti-SARS-CoV-2 antiviral therapeutics: in-silico and in-vitro analysis of edible mushroom- Cordyceps militaris

mycolabadmin

Researchers tested an edible mushroom called Cordyceps militaris to see if it could fight SARS-CoV-2, the virus that causes COVID-19. Using computer modeling and laboratory experiments, they found that a compound in the mushroom called cordycepin strongly attached to the virus’s spike protein and reduced viral numbers by about 50% in cell cultures. The study supports traditional uses of this mushroom and suggests it could be helpful in managing COVID-19 as the disease becomes endemic.

Microbe Profile: Streptomyces formicae KY5: an ANT-ibiotic factory

mycolabadmin

Scientists discovered a special bacterium called Streptomyces formicae living in ant nests in Africa that produces powerful antibiotics effective against dangerous drug-resistant bacteria and fungi. This bacterium has the genetic potential to make at least 45 different antimicrobial compounds, though most are not currently being produced under standard laboratory conditions. Using advanced gene-editing techniques like CRISPR, researchers are working to activate these hidden pathways to discover new medicines. This research demonstrates how exploring bacteria in nature can lead to finding new antibiotics to treat serious infections.

Comparative Efficacy of Antrodia cinnamomea on Liver Function Biomarkers in Mice and Rats: A Network Meta-Analysis

mycolabadmin

This study compared different extracts from a medicinal mushroom called Antrodia cinnamomea to see which ones work best for protecting liver health. Researchers analyzed data from multiple animal studies and found that extracts rich in compounds called triterpenoids were the most effective at improving liver function and reducing inflammation. The findings suggest that this mushroom could potentially become a natural treatment option for liver disease in the future.

Anti-Therapeutic Action: Not mentioned