Anti-Therapeutic Action: None reported

Biocontrol of citrus fungal pathogens by lipopeptides produced by Bacillus velezensis TZ01

Scientists discovered a beneficial bacterium called Bacillus velezensis that can protect citrus fruits from harmful fungi. This bacterium produces natural compounds called lipopeptides that kill disease-causing fungi without the need for chemical fungicides. The lipopeptides are stable and effective across different environmental conditions, making them promising for use in citrus farming as an eco-friendly alternative to traditional pesticides.

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Novel secondary metabolite from a new species of Hypoxylon saxatilis sp. nov. for suppressing bacterial wilt in tomato

Scientists discovered a new type of fungus called Hypoxylon saxatilis that produces a natural compound called tetrahydrofuran. This compound effectively kills the bacteria that cause tomato plants to wilt and die. When used on tomato plants in the greenhouse, this fungal extract reduced disease severity by over 83%, offering a safer, environmentally friendly alternative to chemical pesticides for protecting crops.

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Characterization of the Enzymatic and Biosorption Processes Involved in the Decolorization of Remazol Brilliant Blue R Dye by Pleurotus ostreatus Pellets

This research demonstrates how oyster mushroom pellets can effectively remove harmful synthetic dyes from industrial wastewater through a combination of chemical absorption and enzymatic breakdown. The fungus produces specialized enzymes that degrade the complex dye molecules while also physically absorbing dye particles. This biological approach offers a promising, sustainable alternative to traditional chemical wastewater treatment methods used in the textile industry.

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Inhibitory Effects and Mechanisms of Perilla Essential Oil and Perillaldehyde against Chestnut Pathogen Botryosphaeria dothidea

Chestnuts often rot during storage due to fungal infection. This study found that oil extracted from perilla leaves, particularly a compound called perillaldehyde, effectively prevents the fungus Botryosphaeria dothidea from growing. The antifungal compounds work by breaking down the protective layers of the fungal cells, causing them to leak and die. When applied to stored chestnuts, this natural oil significantly extends their shelf life without harming human health.

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Biological Characteristics and Domestication of Dichomitus squalens and the Antioxidant Activity of Its Cultivated Fruiting Bodies

Researchers cultivated a type of fungus called Dichomitus squalens and extracted beneficial compounds called polysaccharides from its fruiting bodies. These polysaccharides showed strong antioxidant properties, meaning they can help protect cells from damage caused by harmful free radicals. The study identified the best growing conditions for this fungus and developed methods for farming it, suggesting it could become a natural source of antioxidants for health applications.

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Microbiome Analysis Reveals Biocontrol of Aspergillus and Mycotoxin Mitigation in Maize by the Growth-Promoting Fungal Endophyte Colletotrichum tofieldiae Ct0861

Researchers discovered that a beneficial fungal endophyte called Colletotrichum tofieldiae can protect maize crops from contamination by harmful Aspergillus fungi that produce dangerous toxins called aflatoxins. When maize plants were treated with this endophyte either through seed coating or leaf spraying, they grew better and produced higher yields while also experiencing a dramatic 90% reduction in fungal contamination and extremely low aflatoxin levels. The protection mechanism appears to work indirectly by boosting the plant’s own defense systems rather than through direct combat with the pathogenic fungus, offering a sustainable and safe solution for improving crop quality and food safety.

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β-chitosan attenuates hepatic macrophage-driven inflammation and reverses aging-related cognitive impairment

Researchers found that β-chitosan, a compound extracted from squid parietal bone, can reverse age-related memory and learning problems in mice, zebrafish, and worms. The compound works by reducing excessive inflammation in the liver and lowering inflammatory chemicals in the blood, which in turn reduces brain inflammation. This discovery suggests a direct connection between liver health and brain aging, and β-chitosan may offer a new therapeutic approach for age-related cognitive decline.

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Optimization of Ultrasonic Extraction to Obtain Erinacine A and Polyphenols with Antioxidant Activity from the Fungal Biomass of Hericium erinaceus

Researchers developed an efficient ultrasonic extraction method to obtain beneficial compounds from the lion’s mane mushroom (Hericium erinaceus), particularly a substance called erinacine A and antioxidants. The optimized process uses 80% ethanol and takes 45 minutes, producing extracts rich in antioxidants that can protect cells from damage. These extracts showed promise in protecting brain cells and could potentially help prevent or treat neurodegenerative diseases like Alzheimer’s disease.

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Anoectochilus roxburghii Extract Extends the Lifespan of Caenorhabditis elegans through Activating the daf-16/FoxO Pathway

Researchers studied a traditional Asian orchid plant (Anoectochilus roxburghii) and found it can extend the lifespan of laboratory worms by about 16% and help them resist stress from UV light and heat. The plant works by activating a specific genetic pathway that increases the worm’s natural antioxidant defenses, protecting cells from damage. These findings suggest the plant could potentially be developed into anti-aging products for humans.

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Native Bacteria Are Effective Biocontrol Agents at a Wide Range of Temperatures of Neofusicoccum parvum, Associated with Botryosphaeria Dieback on Grapevine

Scientists discovered that native bacteria from Chile, particularly Pseudomonas strains, can effectively control a serious fungus that damages grapevines. These bacteria work across a range of temperatures and successfully reduced fungal growth both in laboratory tests and in actual vineyards. This discovery offers a natural, environmentally-friendly alternative to chemical fungicides for protecting grape crops.

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