None reported – Page 5

Synergistic potential and apoptosis induction of Bunium persicum essential oil and its pure components, cuminaldehyde and γ-terpinene, in combination with fluconazole on Candida albicans isolates: in vitro and in silico evaluation

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Researchers studied how Bunium persicum essential oil and two of its active components work together with the antifungal drug fluconazole to fight resistant Candida yeast infections. They found that cuminaldehyde, one of the oil’s main components, was particularly effective when combined with fluconazole and could trigger yeast cell death. These natural compounds could offer a promising new approach to treating fungal infections that have become resistant to standard medications.

Interference with sexual mating of Sporisorium scitamineum by verrucarin A isolated from Paramyrothecium sp

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Scientists discovered that a naturally occurring fungus called Paramyrothecium sp. produces a compound called verrucarin A that prevents sugarcane smut disease. This compound works by stopping the mating process between fungal spores, preventing the disease from developing without harming the sugarcane plant. Greenhouse experiments showed that using this natural compound reduced disease occurrence from 80% to just 37%, offering a safe and eco-friendly alternative to chemical pesticides for protecting sugarcane crops.

Impact of Clove Oil on Biofilm Formation in Candida albicans and Its Effects on Mice with Candida Vaginitis

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Clove oil, a common kitchen spice, shows promise as a treatment for vaginal yeast infections caused by Candida albicans. The oil contains eugenol, which blocks the fungus’s ability to form protective biofilms and reduces inflammation. In mouse studies, clove oil treatment decreased yeast infection symptoms and lowered inflammatory markers, suggesting it could be a safe, natural alternative to conventional antifungal drugs.

Cestrum tomentosum L.f. Extracts against Colletotrichum scovillei by Altering Cell Membrane Permeability and Inducing ROS Accumulation

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Researchers found that extracts from the Cestrum tomentosum plant effectively kill a fungus that causes anthracnose disease in chili peppers. The plant extract works by damaging the fungal cell membranes and causing harmful reactive oxygen species to accumulate inside fungal cells. This natural remedy showed strong protective and therapeutic effects when applied to chili pepper fruits, offering a safer alternative to synthetic chemical fungicides.

Biocontrol of Cercospora leaf spot in sugar beet by a novel Bacillus velezensis KT27 strain: Enhanced antifungal activity and growth promotion in laboratory and field conditions

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This research demonstrates that a beneficial bacteria called Bacillus velezensis KT27 can effectively control a common fungal disease in sugar beet crops. The bacteria fights the disease by producing natural antifungal compounds and can be further enhanced by exposure to inactivated fungal pathogens. Field trials showed the bacterial treatment provided disease protection almost as good as chemical fungicides while also promoting plant growth and increasing sugar beet yield by up to 15%.

Advances in the extraction, purification, structural characterization, and elucidation of the biological functions of polysaccharides from Hericium erinaceus

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Hericium erinaceus, commonly known as the monkey head mushroom, contains special molecules called polysaccharides that have numerous health benefits. Researchers have found that these polysaccharides can boost immunity, lower cholesterol and blood sugar, fight tumors, reduce inflammation, and promote healthy gut bacteria. Different extraction methods and purification processes can be used to obtain these beneficial compounds, making them useful for developing health supplements and medicines.

Mushroom stem-based diets elicit region-specific shifts in rainbow trout gut microbiota

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Researchers tested whether mushroom stem waste products could be used as sustainable fish feed ingredients. When juvenile rainbow trout were fed diets containing 30% mushroom stems from three different species, their gut bacteria changed in beneficial ways without harming the intestinal lining. Different parts of the gut showed different bacterial responses, with the most beneficial effects being increased growth of helpful bacteria like Mycoplasma and Legionella. This research suggests mushroom processing byproducts could improve aquaculture sustainability while supporting fish health.

Inonotus hispidus Protects against Hyperlipidemia by Inhibiting Oxidative Stress and Inflammation through Nrf2/NF-κB Signaling in High Fat Diet Fed Mice

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Inonotus hispidus is an edible mushroom that may help treat obesity and high cholesterol by reducing fat levels and inflammation in the body. In mice fed a high-fat diet, the mushroom improved cholesterol profiles, reduced liver damage, and promoted beneficial gut bacteria. The beneficial effects appear to work through activating the body’s natural antioxidant defenses and reducing inflammation-causing proteins.

Structure-Forming Properties of Pleurotus ostreatus: A Promising Resource for Edible 3D Printing Applications

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Low-grade oyster mushrooms, which normally go to waste due to cosmetic imperfections, contain valuable nutrients and compounds that make them excellent for 3D food printing. These mushrooms naturally possess properties like chitin and β-glucans that create the right consistency for printing edible structures. Using these discarded mushrooms for innovative 3D printing reduces waste, cuts production costs by up to 75%, and creates nutritious, customizable food products.

Targeting SARS-CoV-2 with Chaga mushroom: An in silico study toward developing a natural antiviral compound

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This study used computer modeling to investigate whether Chaga mushroom components can bind to and potentially block the coronavirus spike protein that SARS-CoV-2 uses to infect cells. The researchers found that three active compounds in Chaga—beta glycan, betulinic acid, and galactomannan—attached strongly to the virus’s binding sites in ways similar to known antiviral molecules. Beyond blocking viral entry, Chaga also has immune-boosting and anti-inflammatory properties that could help prevent the dangerous cytokine storm associated with severe COVID-19.

Anti-Therapeutic Action: None reported