None reported – Page 3

Valorization of Hericium erinaceus By-Products for β-Glucan Recovery via Pulsed Electric Field-Assisted Alkaline Extraction and Prebiotic Potential Analysis

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This research shows how scientists can extract beneficial compounds called β-glucans from leftover Lion’s Mane mushroom material using electrical pulses and alkaline treatment. These extracted compounds work like prebiotics, feeding and promoting the growth of beneficial bacteria in your gut, which then produce healthy fatty acids that support digestive health. The method is environmentally friendly and could help food companies make functional ingredients from mushroom waste.

Isolation of Actinobacteria from Date Palm Rhizosphere with Enzymatic, Antimicrobial, Antioxidant, and Protein Denaturation Inhibitory Activities

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Researchers isolated bacteria called actinobacteria from soil around date palm roots in Algeria’s Sahara Desert. One promising strain, Streptomyces sp. SGI16, was found to produce multiple enzymes and compounds with strong antimicrobial and antioxidant properties. These findings suggest desert microorganisms could be valuable sources for developing new medicines and agricultural products.

Lentinan inhibits melanoma development by regulating the AKT/Nur77/Bcl-2 signaling axis

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This research demonstrates that lentinan, a compound from shiitake mushrooms, can effectively inhibit melanoma (a dangerous skin cancer) in laboratory studies. The compound works by triggering cancer cells to self-destruct through a specific cellular pathway involving three key proteins: AKT, Nur77, and Bcl-2. Importantly, the treatment showed no significant toxic side effects in animal models, suggesting it could be developed as a new cancer therapy option.

Phytochemical Analysis and Anti-Ulcer Potential of Phenolic Compounds of Inonotus nidus-pici Pilát

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Researchers studied a wood mushroom called Inonotus nidus-pici to understand its healing potential. They found it contains beneficial compounds like quercetin and rosmarinic acid that act as antioxidants. When tested on rats with chemically-induced stomach ulcers, the mushroom extract provided protection similar to common ulcer medications, suggesting it could help prevent stomach damage from pain relievers.

Synthesis of silver nanoparticles employing Polyalthia longifolia leaf extract and their in vitro antifungal activity against phytopathogen

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Scientists successfully created tiny silver particles using leaves from the Polyalthia longifolia plant, an evergreen tree native to India. These silver nanoparticles proved highly effective at stopping the growth of Alternaria alternata, a fungus that damages crops and causes leaf spot disease. The method is inexpensive, environmentally friendly, and the particles remain stable for months, making them a promising natural alternative to chemical fungicides for protecting plants.

A novel synbiotic formulation prevents calcium oxalate stones by restoring gut microbiota homeostasis

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This study tested a special probiotic and prebiotic combination to prevent kidney stones caused by too much oxalate in the body. The formula containing three beneficial bacteria strains and a plant-based fiber worked better than any single component alone. The treatment restored healthy gut bacteria, protected the intestinal lining, and reduced the amount of oxalate reaching the kidneys, effectively preventing stone formation in animal models.

Antioxidative Activities of Micronized Solid-State Cultivated Hericium erinaceus Rich in Erinacine A against MPTP-Induced Damages

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Researchers tested a processed form of Lion’s mane mushroom (Hericium erinaceus) to see if it could protect against Parkinson’s disease-like damage in mice. The mushroom mycelium was specially processed to break down cell walls and increase its effectiveness. When given to mice exposed to a Parkinson’s-causing toxin, the mushroom treatment restored dopamine levels and reduced harmful oxidative stress in the brain and liver in a dose-dependent manner.

The protecting role of Ganoderma lucidum polysaccharides on the retinal neurovascular units in rats with retinal ischemia-reperfusion injury

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This research demonstrates that polysaccharides extracted from Ganoderma lucidum mushrooms can protect rat retinas from damage caused by blocked and then restored blood flow. The treatment reduced cell death, decreased harmful oxidative stress, reduced inflammation-like responses from support cells, and improved retinal electrical function. These findings suggest that Ganoderma lucidum could potentially be developed as a therapeutic option for eye diseases like glaucoma and diabetic retinopathy where blood flow to the retina is compromised.

Antioxidant, Antibacterial and Dyeing Potential of Crude Pigment Extract of Gonatophragmium triuniae and Its Chemical Characterization

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Scientists discovered a rare orange-pigment-producing fungus called Gonatophragmium triuniae that has useful medicinal and practical applications. The fungus produces a natural pigment that can kill bacteria, protect against oxidative damage, and effectively dye cotton fabrics without toxic chemicals. The main active compound was identified as a phenoxazine derivative, suggesting potential uses in textiles, pharmaceuticals, and natural cosmetics as a safe alternative to synthetic pigments and antibiotics.

A new highly digestible prescription diet containing Bacillus velezensis DSM 15544, fructo-oligosaccharides, plasma immunoglobulin, yeast and sepiolite for the management of acute diarrhea in dogs—a randomized double-blinded, controlled trial

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Dogs with sudden diarrhea often improve on their own, but a new specialized diet was tested to speed up recovery. The diet contained beneficial bacteria (Bacillus velezensis), fiber that feeds good bacteria (fructo-oligosaccharides), protective proteins from pork plasma, yeast, and a mineral that helps firm up stools. Dogs eating this special diet recovered in about 3-4 days compared to 6 days on a regular digestive diet, with 98% improving within a week versus only 66% with the control diet.

Anti-Therapeutic Action: None reported