Anti-Therapeutic Action: None reported

Biological markers of treatment response to serotonergic psychedelic therapies: a systematic review

This review examines how scientists can predict which patients will benefit most from psychedelic-assisted therapy for depression by measuring biological markers in the brain and blood. Researchers found that certain brain changes and protein levels—particularly involving the amygdala, specific brain regions, and inflammation markers—appear linked to treatment success. While the current studies are small, they suggest that measuring these biological markers could eventually help doctors personalize psychedelic treatments for depression.

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Impact of Hericium erinaceus and Ganoderma lucidum metabolites on AhR activation in neuronal HT-22 cells

This study examined how two medicinal mushrooms, lion’s mane and Reishi, affect nerve cells in the brain. The researchers found that metabolites from these mushrooms don’t harm brain cells and actually boost protective proteins that support cell health and survival. The mushrooms appear to work through a cellular receptor called AhR, which helps facilitate communication between the gut and the brain. These findings suggest that these mushrooms may help support brain function and protect against neurological problems.

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Bioactive Peptides from Quinoa (Chenopodium quinoa Willd.) as Modulators of the Gut Microbiome: A Scoping Review of Preclinical Evidence

This review examines how quinoa and its protein-derived peptides can improve gut health by changing the balance of bacteria in the digestive system. Research shows that quinoa helps boost beneficial bacteria, increases diversity of microbial communities, and promotes production of butyrate, a beneficial compound that supports intestinal health. Different disease conditions show specific improvements, such as reduced harmful bacteria in colitis and better metabolic balance in obesity, suggesting quinoa could be tailored for personalized health interventions.

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Sea buckthorn bioactive metabolites and their pharmacological potential in digestive diseases

Sea buckthorn is an ancient medicinal plant containing hundreds of bioactive compounds that show promise in treating digestive diseases like stomach ulcers, colitis, and liver problems. This comprehensive review of 85 scientific studies found that sea buckthorn’s active ingredients work through multiple mechanisms including reducing inflammation, fighting harmful bacteria, protecting the intestinal lining, and balancing gut bacteria. The research suggests sea buckthorn could become a valuable natural supplement for digestive health, though more clinical trials are needed to confirm optimal doses and long-term effectiveness in humans.

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Nanoemulsion formulation of lemongrass essential oil using Pseudomonas-derived rhamnolipids for targeted phytopathogen suppression

This study developed a nano-sized formulation of lemongrass oil stabilized with naturally-derived rhamnolipid surfactant to fight plant fungal diseases. The formulation successfully inhibited the growth of three major plant pathogens and remained stable during storage. This bio-based approach offers farmers an environmentally-friendly alternative to synthetic chemical fungicides for protecting crops.

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Investigating the Neuroprotective, Hepatoprotective, and Antimicrobial Effects of Mushroom Extracts

This study examined four types of edible mushrooms to see if they could protect against aging and fight harmful bacteria. Researchers gave mice an aging-inducing substance and then treated them with mushroom extracts. The mushrooms, particularly Lion’s Mane (Hericium erinaceus), helped prevent brain and liver damage, reduced inflammation, and showed antibacterial effects against multiple bacterial strains. These findings suggest mushrooms could be useful natural supplements to promote health and combat age-related decline.

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Structural Elucidation of Heteropolysaccharides from the Peach-Shaped Dictyophora indusiata and Its Anti-Inflammatory Activity

Researchers extracted polysaccharides from peach-shaped bamboo fungus (Dictyophora indusiata) and discovered they contain beneficial beta-glucans. When tested on human immune cells triggered to become inflamed, these polysaccharides reduced inflammatory markers and messenger proteins. The compounds were found to be chemically stable under various conditions, suggesting potential use as a natural anti-inflammatory supplement or food ingredient.

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Nutraceutical supplement slim reshaped colon histomorphology and reduces Mucispirillum schaedleri in obese mice

Researchers tested a supplement called Slim containing natural compounds like berberine, coenzyme Q10, and beet pulp on obese mice. After 4 weeks, the supplement improved cholesterol and triglyceride levels, increased beneficial gut bacteria, and strengthened the intestinal barrier. The results suggest this combination of natural ingredients works together synergistically to improve gut health and metabolic function in obesity.

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The Inhibitory Effects of Cordyceps militaris ARA301 Extract on Lipopolysaccharide-Induced Lung Injury in vivo

Researchers tested a mushroom extract from Cordyceps militaris to see if it could protect mice from lung injury caused by bacterial toxins. The extract successfully reduced inflammation, prevented excessive mucus production, and decreased immune cell buildup in the lungs. These findings suggest that this mushroom extract could potentially be used as a natural supplement to help prevent respiratory diseases and support lung health.

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