Anti-Therapeutic Action: None mentioned

Harmonizing Nature, Education, Engineering and Creativity: An Interdisciplinary Educational Exploration of Engineered Living Materials, Artistry and Sustainability Using Collaborative Mycelium Brick Construction

This study shows how middle-school students can learn science, engineering, and art together by growing and building with mycelium, a fungal material that can replace plastic and other harmful materials. Students designed shapes, created molds, cultivated living mycelium bricks under sterile conditions, and assembled them into an artistic structure. The hands-on experience helped students develop practical skills like precise measuring and 3D thinking while learning about sustainability and nature’s cycles.

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Designers join scientists to make living architecture a reality

Scientists and designers are working together to create buildings made with living organisms like yeast and fungi that can clean the air, detect hazards, and even repair themselves. These living walls work similar to plants, requiring water and nutrients while providing benefits like removing harmful chemicals and improving air quality. This approach combines nature with architecture to create healthier, more sustainable homes and buildings for the future.

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Haplotype-Phased Chromosome-Level Genome Assembly of Floccularia luteovirens Provides Insights into Its Taxonomy, Adaptive Evolution, and Biosynthetic Potential

Scientists have created the most detailed genetic map of the yellow mushroom (Floccularia luteovirens), a highly valued medicinal and edible fungus from the Tibetan Plateau. Using advanced sequencing technology, they mapped its 13 chromosomes and identified 15 pathways that the mushroom uses to make potentially useful healing compounds. The research also solved a long-standing mystery about the mushroom’s family tree, proving it is not actually related to Armillaria mushrooms as previously thought. This genetic blueprint opens new possibilities for developing medicines from this special fungus.

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Streptomyces-Based Bioformulation to Control Wilt of Morchella sextelata Caused by Pestalotiopsis trachicarpicola

Researchers isolated two beneficial bacteria strains (Streptomyces) from soil around morel mushrooms that can effectively fight a fungal disease causing morel wilting. These bacteria produce natural compounds that kill the disease-causing fungus while also promoting healthier mushroom growth. When used in field tests, these bacterial treatments reduced disease and increased morel yield by nearly 30% compared to untreated crops, offering an eco-friendly alternative to chemical fungicides.

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Misconception of Schizophyllum commune strain 20R-7-F01 origin from subseafloor sediments over 20 million years old

Researchers questioned whether a fungus found in ancient ocean sediments 2 km below the seafloor actually came from 20 million years ago or was modern contamination. By analyzing DNA repetitive sequences in different fungal populations, they discovered the strain was genetically almost identical to modern fungi from Asia, not ancient at all. The extreme conditions in the deep sediments would make it impossible for fungi to survive or exchange genes for millions of years, proving the fungus came from surface contamination during drilling rather than ancient times.

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Optimisation and Characterisation of Novel Angiotensin-Converting Enzyme Inhibitory Peptides Prepared by Double Enzymatic Hydrolysis from Agaricus bisporus Scraps

Scientists discovered three new peptides in common button mushroom scraps that can lower blood pressure by blocking an enzyme called ACE. Using special enzymes to break down mushroom proteins and then purifying the result, they created peptides with strong blood pressure-lowering activity that survive stomach digestion well. This finding turns mushroom waste into a valuable source for making natural blood pressure medications that are safer than synthetic alternatives.

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Updated Taxonomy of Chinese Craterellus (Hydnaceae, Cantharellales) with Three New Species Described

Scientists have discovered and described three new species of trumpet mushrooms (Craterellus) found in China. These mushrooms are valuable because they form helpful relationships with trees and have medicinal properties. By studying both the physical characteristics and DNA of 109 mushroom samples, researchers identified seventeen different Craterellus species in China, greatly expanding our understanding of this important group of edible fungi.

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Synergistic target network construction and dynamic simulation analysis based on a prospective systems pharmacology strategy

Researchers used computer-based methods to study how Sang Huang, a traditional medicinal fungus, might help treat type 2 diabetes. They identified 17 active compounds in the fungus and found that a key component called estradiol dipropionate could improve insulin sensitivity and glucose control by activating specific protein pathways. The study suggests Sang Huang could be a promising natural treatment for diabetes, though more laboratory and animal testing is needed.

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First Step on the Way to Identify Dermatophytes Using Odour Fingerprints

Researchers have developed a new method to quickly identify fungal skin infections caused by dermatophytes by detecting the unique smells (volatile compounds) they produce. Instead of waiting days or weeks for culture-based tests, this approach uses advanced chemical analysis to create a fingerprint of the fungus based on its odor. The study analyzed 47 different dermatophyte strains and found that each species and even individual strains have distinctive chemical signatures, which could one day allow doctors to diagnose infections rapidly using portable devices similar to electronic noses.

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Silver Chloride Precipitation-limiting Factor for Accurate Silver Determination in Ag-accumulating Mushrooms After Nitric Acid Digestion

This research addresses a critical problem in measuring silver content in certain mushrooms, particularly silver-accumulating Amanita species. Scientists discovered that standard laboratory digestion procedures using nitric acid can cause silver to precipitate as silver chloride, making it invisible to measurement instruments and leading to false low results. The study demonstrates that neutron activation analysis is more accurate for measuring silver in these mushrooms, or alternatively, specialized multi-step digestion procedures can dissolve the precipitated silver chloride to obtain accurate measurements.

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