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Study on the inhibitory mechanism of fig leaf extract against postharvest Fusarium in melon

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Researchers discovered that fig leaves contain natural compounds that can prevent fruit rot caused by Fusarium fungus in melons. When applied to infected melons, the fig leaf extract kills the fungus by damaging its cell membranes and overwhelming it with harmful molecules called reactive oxygen species. This natural treatment could replace chemical fungicides that harm the environment and leave residues on food, offering a safer way to preserve melons during transport and storage.

Antioxidant and Enzyme Inhibitory Potential of Streptomyces sp. G-18 Grown in Various Media

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Researchers studied bacteria called Streptomyces that were isolated from high mountains in Nepal to see if they could produce useful compounds. They grew these bacteria in four different types of growth media and tested the resulting extracts for antioxidant properties and ability to block harmful enzymes. They found that the choice of growth medium significantly affected what compounds the bacteria produced, with one medium (R2YE) being especially effective at producing compounds that could help treat diseases like Alzheimer’s and diabetes.

Dynamic proteomic changes and ultrastructural insights into Pochonia chlamydosporia’s parasitism of Parascaris equorum eggs

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Scientists studied how a special fungus called Pochonia chlamydosporia attacks and destroys parasitic worm eggs. Using advanced microscopy and protein analysis, they tracked the fungus through three stages of infection and identified the specific proteins and processes it uses to break down the worm eggs. This research helps us understand how this fungus works so it can be better used as a natural pest control method to protect animals from harmful parasites.

Metabolic profiling of endophytic fungi acting as antagonists of the banana pathogen Colletotrichum musae

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Scientists found three special fungi living inside rainforest plants in the Philippines that can fight the fungus causing banana rot. These endophytic fungi produce chemical compounds that stop the disease-causing fungus from growing, offering a natural alternative to traditional fungicides. The researchers found that the type of growing medium affects which compounds these fungi produce, and two promising strains could potentially be used to reduce fruit losses during storage and transport.

Terpinen-4-ol triggers autophagy activation and metacaspase-dependent apoptosis against Botrytis cinerea

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Terpinen-4-ol, a natural compound from tea tree oil, effectively kills gray mold fungus that spoils fruits and vegetables after harvest. The compound works by damaging fungal cell membranes, creating harmful reactive molecules inside fungal cells, and triggering the fungal cells’ self-destruction pathways. When tested on tomatoes and strawberries, terpinen-4-ol successfully reduced mold growth and disease spread, suggesting it could be a safe, eco-friendly alternative to chemical fungicides for protecting fresh produce.

Draft genome sequence of three Glaciozyma watsonii strains isolated from near the Syowa station area, East Antarctica

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Scientists have sequenced the genetic code of three strains of a special cold-loving yeast called Glaciozyma watsonii found in East Antarctica. This yeast can grow in extremely cold conditions, even at temperatures below freezing, which is remarkable. Understanding its genome may help scientists develop new medicines and discover enzymes that work in cold conditions.

Valorization of various lignocellulosic wastes to Ganoderma lucidum (Curtis) P. Karst (Reishi Mushroom) cultivation and their FT-IR assessments

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This research demonstrates how agricultural and forestry waste materials can be effectively converted into nutritious Reishi mushrooms through sustainable cultivation practices. Oak wood substrates produced the highest mushroom yields, while various agricultural wastes showed promising results for producing medicinal mushrooms. Using specialized spectroscopy techniques, scientists confirmed that the Reishi mushroom effectively breaks down and utilizes the complex plant materials in these waste substrates. This approach offers an environmentally friendly solution to waste management while producing valuable medicinal mushrooms.

A Zn2-Cys6 transcription factor, TgZct4, reprograms antioxidant activity in the fungus Trichoderma guizhouense to defend against oxidative stress

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Researchers discovered a key protein switch in a beneficial fungus called Trichoderma guizhouense that helps it survive harmful oxidative stress. This fungus is used as a natural pesticide to protect crops from disease. The protein, called TgZct4, acts like a master controller that turns on the fungus’s defense systems when it encounters damaging chemical stress, making it more resilient and effective at protecting plants.

Insights into microbiome-triterpenoid correlation in Poria cocos via comparative analysis of sclerotial and soil microenvironments

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Researchers discovered that the medicinal fungus Poria cocos creates its own specialized microbial environment in its underground structure that is closely linked to the production of pachymic acid, a compound with anti-cancer and immune-boosting properties. By comparing the microbes living in the fungus versus surrounding soil, they found specific beneficial bacteria and fungi that thrive in the fungus but are rare in soil. This discovery could help improve cultivation techniques to produce higher quality medicinal fungi with more therapeutic compounds.

Miniaturized high-throughput conversion of fungal strain collections into chemically characterized extract libraries for antimicrobial discovery

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Scientists developed a fast, automated method called FLECS-96 to screen hundreds of fungal species for antimicrobial compounds in a small 96-well plate format. The method combines fungal culture, chemical extraction, and analysis to identify promising candidates against resistant bacteria like Staphylococcus aureus. The team successfully identified two bioactive compounds from the fungi tested. This innovation could significantly speed up the discovery of new antibiotics to combat antibiotic-resistant infections.

Anti-Therapeutic Action: None mentioned