none explicitly mentioned

Indole-Based Compounds as Potential Drug Candidates for SARS-CoV-2

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Scientists are searching for new treatments for COVID-19 by studying indole-containing compounds, which are found in many plants and can be made in laboratories. Some approved drugs with indole structures, like the antiviral drug Arbidol, have been repurposed to fight COVID-19. Researchers are also designing new indole compounds and using computer simulations to predict which ones might work best against the virus’s key proteins.

Scanning electron microscopy of hyphal ectobiont bacteria within mycelial extracellular matrices

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Researchers studied how bacteria (Bacillus subtilis) attach to mushroom fungi (Lion’s Mane/Hericium erinaceus) in liquid cultures. Using a special drying technique and electron microscopy, they were able to see tiny structures where bacteria stick to the fungal threads. These structures are made of slimy substances produced by the fungus and could potentially allow bacteria to influence the fungus’s electrical and physical properties.

Tyrosinase Inhibitors Derived from Chemical Constituents of Dianella ensifolia

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Researchers isolated four new plant compounds and 67 known compounds from Dianella ensifolia, a traditional Asian medicinal plant. Two of these compounds (11 and 14) were found to inhibit tyrosinase, the enzyme responsible for melanin production, making them approximately 13 times more effective than arbutin, a common cosmetic whitening ingredient. These findings suggest that D. ensifolia could be developed as a natural source of skin-whitening agents for treating age spots, freckles, and other pigmentation disorders.

Anti-Therapeutic Action: none explicitly mentioned

Indole-Based Compounds as Potential Drug Candidates for SARS-CoV-2

Scanning electron microscopy of hyphal ectobiont bacteria within mycelial extracellular matrices

Tyrosinase Inhibitors Derived from Chemical Constituents of Dianella ensifolia