Anti-Therapeutic Action: mutations in critical residues impair fungal development and secondary metabolism

Resolving the fungal velvet domain architecture by Aspergillus nidulans VelB

Scientists studied how fungi use special proteins called velvet regulators to control their growth and produce protective chemicals. By examining these proteins in different fungi and using genetic techniques, they found that two specific amino acids are critical for these proteins to interact with each other. This discovery helps explain how fungi coordinate their development with the production of important chemicals, which could eventually help control harmful fungi or improve industrial fungal applications.

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